Background Depression is the leading cause of disability worldwide with> 50% of cases
emerging before the age of 25 years. Large-scale neuroimaging studies in depression …

Objective Neuroimaging findings have been reported in regions of the brain associated with
emotion in both adults and adolescents with depression, but few studies have investigated …

Major depressive disorder (MDD) often emerges during adolescence with detrimental effects
on development as well as lifetime consequences. Identifying neurobiological markers that …

Adolescents comprise one fourth of the world's population, with about 90% of them living in
low-and middle-income countries (LMICs). The incidence of depression markedly increases …

This paper reviews prior research studies examining neurobiological correlates and
treatment response of depression in children, adolescents, and adults. Although there are …

The neuro-anatomical substrates of major depressive disorder (MDD) are still not well
understood, despite many neuroimaging studies over the past few decades. Here we …

Adolescent depression is associated with increased risk for suicidality, social and
educational impairment, smoking, substance use, obesity, and depression in adulthood. It is …

Background Adequate and timely identification of depression is essential to improve patient
care. A potential method to achieve this is by using neuroimaging. Many neuroimaging …

Importance Adolescent major depressive disorder (MDD) is associated with serious adverse
implications for brain development and higher rates of self-injury and suicide, raising …

Background Adolescent-onset depressive disorders (DDs) are associated with deficits in the
regulation of negative affect across modalities (self-report, behavioral paradigms, and …