The immune system is essential for maintaining a delicate balance between eliminating
pathogens and maintaining tolerance to self‐tissues to avoid autoimmunity. An enormous …

To maintain health, the immune system must maintain a delicate balance between
eliminating invading pathogens and avoiding immune disorders such as autoimmunity and …

Keeping a delicate balance in the immune system by eliminating invading pathogens, while
still maintaining self-tolerance to avoid autoimmunity, is critical for the body's health. The gut …

In humans, a complex interaction between the host immune system and commensal
microbiota is required to maintain gut homeostasis. In this symbiotic relationship, the …

The gastrointestinal tract is home to the largest microbial population in the human body. The
gut microbiota plays significant roles in the development of the gut immune system and has …

The composition of a host's intestinal microbiota directs the type of mucosal and systemic
immune responses by affecting the proportion and number of functionally distinct T cell …

The gut microbiota plays a major role in the developmental biology and homeostasis of cells
belonging to the adaptive and innate arms of the immune system. Alterations in its …

The intestinal microbiota plays a crucial role in influencing the development of host
immunity, and in turn the immune system also acts to regulate the microbiota through …

The interplay between the immune response and the gut microbiota is complex. Although it
is well-established that the gut microbiota is essential for the proper development of the …

Autoimmune diseases have long been known to share a common pathogenesis involving a
dysregulated immune system with a failure to recognize self from non-self-antigens. This …