Community-wide transcriptome of the oral microbiome in subjects with and without periodontitis

AE Duran-Pinedo, T Chen, R Teles, JR Starr… - The ISME …, 2014 - academic.oup.com
Despite increasing knowledge on phylogenetic composition of the human microbiome, our
understanding of the in situ activities of the organisms in the community and their …

Metagenomic sequencing reveals microbiota and its functional potential associated with periodontal disease

J Wang, J Qi, H Zhao, S He, Y Zhang, S Wei, F Zhao - Scientific reports, 2013 - nature.com
Although attempts have been made to reveal the relationships between bacteria and human
health, little is known about the species and function of the microbial community associated …

Has the use of molecular methods for the characterization of the human oral microbiome changed our understanding of the role of bacteria in the pathogenesis of …

WG Wade - Journal of clinical periodontology, 2011 - Wiley Online Library
Wade WG. Has the use of molecular methods for the characterization of the human oral
microbiome changed our understanding of the role of bacteria in the pathogenesis of …

Microbiota and metatranscriptome changes accompanying the onset of gingivitis

EM Nowicki, R Shroff, JA Singleton, DE Renaud… - MBio, 2018 - Am Soc Microbiol
Over half of adults experience gingivitis, a mild yet treatable form of periodontal disease
caused by the overgrowth of oral microbes. Left untreated, gingivitis can progress to a more …

Deep sequencing of the oral microbiome reveals signatures of periodontal disease

B Liu, LL Faller, N Klitgord, V Mazumdar, M Ghodsi… - PloS one, 2012 - journals.plos.org
The oral microbiome, the complex ecosystem of microbes inhabiting the human mouth,
harbors several thousands of bacterial types. The proliferation of pathogenic bacteria within …

Impact of systemic factors in shaping the periodontal microbiome

F Teles, Y Wang, G Hajishengallis… - Periodontology …, 2021 - Wiley Online Library
Since 2010, next‐generation sequencing platforms have laid the foundation to an exciting
phase of discovery in oral microbiology as it relates to oral and systemic health and disease …

Metatranscriptomics of the human oral microbiome during health and disease

P Jorth, KH Turner, P Gumus, N Nizam, N Buduneli… - MBio, 2014 - Am Soc Microbiol
The human microbiome plays important roles in health, but when disrupted, these same
indigenous microbes can cause disease. The composition of the microbiome changes …

Defining functional signatures of dysbiosis in periodontitis progression

GP Wang - Genome medicine, 2015 - Springer
Periodontitis is a common inflammatory disease that leads to tooth loss and has been linked
to cardiovascular disease and diabetes mellitus. The periodontal microbiome is highly …

High-resolution taxonomic profiling of the subgingival microbiome for biomarker discovery and periodontitis diagnosis

SP Szafranski, ML Wos-Oxley… - Applied and …, 2015 - Am Soc Microbiol
The oral microbiome plays a key role for caries, periodontitis, and systemic diseases. A
method for rapid, high-resolution, robust taxonomic profiling of subgingival bacterial …

Dysbiosis and alterations in predicted functions of the subgingival microbiome in chronic periodontitis

ME Kirst, EC Li, B Alfant, YY Chi, C Walker… - Applied and …, 2015 - Am Soc Microbiol
Chronic periodontitis is an inflammatory disease of the periodontium affecting nearly 65
million adults in the United States. Changes in subgingival microbiota have long been …