The integrative conjugative element (ICE) Tn 5253 of Streptococcus pneumoniae, conferring
resistance to tetracycline and chloramphenicol, was found integrated at a 83-bp specific …

Conjugative transposon Tn 5253, an integrative conjugative element (ICE) of Streptococcus
pneumoniae carrying the cat and tet (M) genes, was shown to be 64,528 bp in size and to …

Abstract Background Tn 5253, a composite Integrative Conjugative Element (ICE) of
Streptococcus pneumoniae carrying tet (M) and cat resistance determinants, was found to (i) …

Tn5251 belongs to the Tn916-Tn1545 family of conjugative transposons (CT) and was found
integrated into CT Tn5252, to form the composite element Tn5253 of Streptococcus …

We have cloned and mapped a 69-kilobase (kb) region of the chromosome of Streptococcus
pneumoniae DP1322, which carries the conjugative omega (cat-tet) insertion from S …

Multidrug resistance in Streptococcus pneumoniae (or pneumococcus) continues to be a
global challenge. An important class of antibiotic resistance determinants disseminating in …

Objectives To investigate the genetic basis of catQ-mediated chloramphenicol resistance in
Streptococcus agalactiae. Methods Two clinical strains of catQ-positive chloramphenicol …

The linkage between the macrolide efflux gene mef (I) and the chloramphenicol inactivation
gene catQ was first described in Streptococcus pneumoniae (strain Spn529), where the two …

Mobile genetic elements (MGEs), such as integrative and conjugative elements (ICEs),
plasmids and translocatable units (TUs), are important drivers for the spread of antibiotic …

Pneumococcal resistance to tetracycline, chloramphenicol, erythromycin and clindamycin is
often attributed to carriage of conjugative transposons of the Tn916 family. The less well …