The tumor-specific targeting of cancerostatics using polymer drug carriers represents a
potential strategy to achieve an effective treatment with reduced side toxicity. Synthetic water …

Data on the synthesis, physicochemical characterisation and in vitro and in vivo biological
properties of the new, nontargeted or antibody-targeted polymer–doxorubicin conjugates …

Copolymers of N-(2-hydroxypropyl) methacrylamide (HPMA) are prototypic and well-
characterized polymeric drug carriers that have been broadly implemented in the delivery of …

The molecular weight and molecular architecture of soluble polymer drug carriers
significantly influence the biodistribution and anti‐tumour activities of their doxorubicin …

Various conjugates of anticancer drug doxorubicin (DOX) covalently attached via
hydrolytically degradable hydrazone bond to water-soluble N-(2-hydroxypropyl) …

Polymer drug carriers that are based on N-(2-hydroxypropyl) methacrylamide (HPMA)
copolymers have been widely used in the development and synthesis of high-molecular …

Over the past few decades, numerous polymer drug carrier systems are designed and
synthesized, and their properties are evaluated. Many of these systems are based on water …

Herein, new biodegradable star polymer–doxorubicin conjugates designed for passive
tumor targeting were investigated, and their synthesis, physico-chemical characterization …

Synthesis, physicochemical behavior, tumor accumulation and preliminary anticancer
activity of a new biodegradable graft copolymer–doxorubicin (DOX) conjugates designed for …

Purpose In vivo efficacy and safety of HPMA-based copolymers armed with doxorubicin via
a spacer containing pH-sensitive linkage that can be prepared within a broad range of …