Over the past 50 years there has been a virtual revolution in thinking about risk mechanisms.
The key areas of challenge and opportunity include: identification of environmental causes; …

Behavioral genetic research has concluded that the more important environmental
influences result in differences between siblings (referred to as nonshared; e²), whereas …

There has been considerable interest in generenvironment (GrE) interactions in psychiatric
genetics since studies by Caspi and colleagues (Caspi et al. 2002, 2003) suggested that …

Most common diseases demonstrate familial aggregation; the ratio of the risk for relatives of
affected people to the risk for relatives of unaffected people (the familial risk ratio))> 1. This …

Evidence is growing that pre-and perinatal exposures and factors play a role in not only
childhood but adulthood disorders. Therefore, there is a compelling need to undertake a …

Polygenic scores have recently been used to summarise genetic effects among an
ensemble of markers that do not individually achieve significance in a large-scale …

Complex neurodevelopmental disorders, such as schizophrenia, autism, attention deficit
(hyperactivity) disorder,(manic) depressive illness and addiction, are thought to result from …

OBJECTIVE: Child and adolescent psychiatry is rife with examples of the sustained effects of
early experience on brain function. The study of behavioral genetics provides evidence for a …

A major benchmark in the understanding of psychiatric illness in children and adolescents,
Developmental Psychopathology and Wellness reports on progress in identifying genetic …

Background Low socioeconomic status (SES) is associated with increased risk for emotional
and behavioural problems among children. Evidence from twin studies has shown that …