The post-acute phase of SARS-CoV-2 infection in two macaque species is associated with signs of ongoing virus replication and pathology in pulmonary and …

KP Böszörményi, MA Stammes, ZC Fagrouch… - Viruses, 2021 - mdpi.com
The post-acute phase of SARS-CoV-2 infection was investigated in rhesus (Macaca mulatta)
and cynomolgus macaques (Macaca fascicularis). During the acute phase of infection …

Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in lungs of African green monkeys

E Speranza, BN Williamson, F Feldmann… - Science translational …, 2021 - science.org
Detailed knowledge about the dynamics of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection is important for uncovering the viral and host factors that contribute …

SARS-CoV-2 RNA persists in the central nervous system of non-human primates despite clinical recovery

H Li, KA McLaurin, CF Mactutus, J Rappaport… - Molecular …, 2023 - Springer
The post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection is a multisystemic condition characterized by the persistence or emergence of …

Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques

C Shan, YF Yao, XL Yang, YW Zhou, G Gao, Y Peng… - Cell research, 2020 - nature.com
The 2019 novel coronavirus (SARS-CoV-2) outbreak is a major challenge for public health.
SARS-CoV-2 infection in human has a broad clinical spectrum ranging from mild to severe …

Histologic pulmonary lesions of SARS-CoV-2 in 4 nonhuman primate species: an institutional comparative review

CS Clancy, C Shaia, V Munster, E de Wit… - Veterinary …, 2022 - journals.sagepub.com
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is an emergent, amphixenotic infection that resulted in a …

Comparison of SARS-CoV-2 infections among 3 species of non-human primates

S Lu, Y Zhao, W Yu, Y Yang, J Gao, J Wang, D Kuang… - BioRxiv, 2020 - biorxiv.org
Abstract COVID-19, caused by SARS-CoV-2 infection, has recently been announced as a
pandemic all over the world. Plenty of diagnostic, preventive and therapeutic knowledges …

Comparison of subgenomic and total RNA in SARS-CoV-2-challenged rhesus macaques

G Dagotto, NB Mercado, DR Martinez, YJ Hou… - Journal of …, 2021 - Am Soc Microbiol
Respiratory virus challenge studies involve administration of the challenge virus and
sampling to assess for protection in the same anatomical locations. It can therefore be …

Subcellular detection of SARS-CoV-2 RNA in human tissue reveals distinct localization in alveolar type 2 pneumocytes and alveolar macrophages

KK Acheampong, DL Schaff, BL Emert, J Lake… - MBio, 2022 - Am Soc Microbiol
The widespread coronavirus disease 2019 (COVID-19) is caused by infection with the novel
coronavirus SARS-CoV-2. Currently, we have limited understanding of which cells become …

Intranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence …

RW Cross, KN Agans, AN Prasad, V Borisevich… - Virology journal, 2020 - Springer
We recently reported the development of the first African green monkey (AGM) model for
COVID-19 based on a combined liquid intranasal (in) and intratracheal (it) exposure to …

COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions

E Urano, T Okamura, C Ono, S Ueno… - Proceedings of the …, 2021 - National Acad Sciences
The pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a
global threat to human health and life. A useful pathological animal model accurately …