Emerging variants of concern (VOC) raise obstacles in shaping vaccination strategies and
ending the pandemic. Vaccinated SARS-CoV-2 convalescence shapes the current immune …

Despite previous coronavirus disease 2019 (COVID-19) vaccinations and severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, SARS-CoV-2 still causes a …

The factors responsible for the spectrum of coronavirus 19 (COVID-19) disease severity and
the genesis and nature of protective immunity against COVID-19 remain elusive. Multiple …

Objective The dynamic adaptive immune responses elicited by the inactivated virus vaccine
CoronaVac remain elusive. Methods In a prospective cohort of 100 healthcare professionals …

Background COVID-19 mRNA vaccines elicit strong T and B cell responses to the SARS-
CoV-2 spike glycoprotein in both SARS-CoV-2 naïve and experienced patients. However, it …

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
highlights the importance of determining the breadth and durability of humoral immunity to …

The immune response promoted by SARS-CoV-2 vaccination is relevant to develop novel
vaccines and optimized prevention strategies. We analyzed the adaptive immunity in healthy …

Our understanding of immune responses to SARS-CoV-2 and variants of concern (VOCs)
has been primarily acquired through analysis of Spike-specific IgG responses. However, a …

Background Adaptive immune response has been thought to play a key role in SARS-CoV-2
infection. The role of B cells, CD4+ T, and CD8+ T cells are different in vaccine-induced …

The inability of patients with CVID to mount specific antibody responses to pathogens has
raised concerns on the risk and severity of SARS-CoV-2 infection, but there might be a role …