Animal models of lassa fever
Lassa virus (LASV), the causative agent of Lassa fever, is estimated to be responsible for up
to 300,000 new infections and 5000 deaths each year across Western Africa. The most …
to 300,000 new infections and 5000 deaths each year across Western Africa. The most …
Pathogenicity and virulence mechanisms of Lassa virus and its animal modeling, diagnostic, prophylactic, and therapeutic developments
HL Murphy, H Ly - Virulence, 2021 - Taylor & Francis
Lassa fever (LF) is a deadly viral hemorrhagic disease that is endemic to West Africa. The
causative agent of LF is Lassa virus (LASV), which causes approximately 300,000 infections …
causative agent of LF is Lassa virus (LASV), which causes approximately 300,000 infections …
Combating Lassa fever in West African sub-region: Progress, challenges, and future perspectives
Lassa fever (LF) is a rodent-borne disease that threatens human health in the sub-region of
West Africa where the zoonotic host of Lassa virus (LASV) is predominant. Currently …
West Africa where the zoonotic host of Lassa virus (LASV) is predominant. Currently …
The search for animal models for Lassa fever vaccine development
IS Lukashevich - Expert review of vaccines, 2013 - Taylor & Francis
Lassa virus (LASV) is the most prevalent arenavirus in West Africa and is responsible for
several hundred thousand infections and thousands of deaths annually. The sizeable …
several hundred thousand infections and thousands of deaths annually. The sizeable …
Differential pathogenesis of closely related 2018 Nigerian outbreak clade III Lassa virus isolates
Nigeria continues to experience ever increasing annual outbreaks of Lassa fever (LF). The
World Health Organization has recently declared Lassa virus (LASV) as a priority pathogen …
World Health Organization has recently declared Lassa virus (LASV) as a priority pathogen …
[HTML][HTML] Vaccine platforms for the prevention of Lassa fever
J Purushotham, T Lambe, SC Gilbert - Immunology Letters, 2019 - Elsevier
Lassa fever is an acute viral haemorrhagic illness caused by Lassa virus (LASV), which is
endemic throughout much of West Africa. The virus primarily circulates in the Mastomys …
endemic throughout much of West Africa. The virus primarily circulates in the Mastomys …
Lassa fever—the road ahead
RF Garry - Nature Reviews Microbiology, 2023 - nature.com
Lassa virus (LASV) is endemic in the rodent populations of Sierra Leone, Nigeria and other
countries in West Africa. Spillover to humans occurs frequently and results in Lassa fever, a …
countries in West Africa. Spillover to humans occurs frequently and results in Lassa fever, a …
Advanced vaccine candidates for Lassa fever
IS Lukashevich - Viruses, 2012 - mdpi.com
Lassa virus (LASV) is the most prominent human pathogen of the Arenaviridae. The virus is
transmitted to humans by a rodent reservoir, Mastomys natalensis, and is capable of causing …
transmitted to humans by a rodent reservoir, Mastomys natalensis, and is capable of causing …
Current research for a vaccine against Lassa hemorrhagic fever virus
Lassa virus (LASV) is a rodent-borne arenavirus endemic to several West African countries
that causes Lassa fever (LF). LF is typically mild but it can cause severe disease …
that causes Lassa fever (LF). LF is typically mild but it can cause severe disease …
[PDF][PDF] Understanding Lassa fever virus and diversification of the rodent vector in the tropics
Conclusion: Advancing knowledge significantly improves our understanding of lassa virus
biology, as well as the mechanisms that allow the virus to evade the host's immune system …
biology, as well as the mechanisms that allow the virus to evade the host's immune system …