Hemodynamic and neurohumoral effects of carperitide (alpha-human atrial natriuretic peptide) in dogs with low-output heart failure

T Hidaka, M Furuya, Y Tani, T Ohno - Nihon yakurigaku zasshi …, 1995 - europepmc.org
We examined the hemodynamic and neurohumoral effects of carperitide in dogs with low-
output heart failure (LHF) produced by volume expansion, ligation of the left anterior …

Effects of carperitide (alpha-human atrial natriuretic peptide) on acute congestive heart failure in dogs

T Hidaka, K Aisaka, T Ohno… - Nihon Yakurigaku zasshi …, 1993 - europepmc.org
Effects of carperitide (alpha-human atrial natriuretic peptide) on hemodynamics and renal
function in dogs with congestive heart failure (CHF) produced by volume expansion and …

Effect of carperitide (alpha-human atrial natriuretic polypeptide) on the cardiovascular system in experimental animals

T Hidaka, K Aisaka, N Inomata, M Furuya… - Nihon Yakurigaku …, 1993 - europepmc.org
The cardiovascular and diuretic actions of carperitide were studied in experimental animals.
Carperitide relaxed various canine arteries and veins that were contracted by high K+ or …

Usefulness of carperitide for the treatment of refractory heart failure due to severe acute myocardial infarction

M Kikuchi, M Nakamura, T Suzuki, M Sato… - Japanese heart …, 2001 - jstage.jst.go.jp
Carperitide (synthetic atrial natriuretic peptide) is a newly developed drug for the treatment
of heart failure. Although this drug has been used for various types of heart failure, it remains …

Marked and prompt hemodynamic improvement by carperitide in refractory congestive heart failure due to dilated cardiomyopathy

M Kikuchi, M Nakamura, T Suzuki, K Ohira… - Japanese heart …, 2000 - jstage.jst.go.jp
SUMMARY A 16-year-old Japanese male diagnosed with congestive heart failure (CHF)
due to dilated cardiomyopathy was treated by conventional intensive treatment such as …

Effects of atrial natriuretic peptide on left ventricular performance in conscious dogs before and after pacing-induced heart failure

N Ohte, CP Cheng, M Suzuki, WC Little - Journal of Pharmacology and …, 1999 - ASPET
Atrial natriuretic peptide (ANP) has potent vasodilatory and natriuretic actions and may have
therapeutic benefit in congestive heart failure (CHF). These benefits may be offset by a …

Preischemic infusion of alpha-human atrial natriuretic peptide elicits myoprotective effects against ischemia reperfusion in isolated rat hearts

H Okawa, H Horimoto, S Mieno, Y Nomura… - Molecular and cellular …, 2003 - Springer
Carperitide, a synthetic alpha-human atrial natriuretic peptide (ANP) is a newly developed
drug for the treatment of heart failure. However, effects of carperitide on susceptibility to …

Inhibition of aldosterone and endothelin-1 by carperitide was attenuated with more than 1 week of infusion in patients with congestive heart failure

C Ishikawa, T Tsutamoto, A Wada, M Fujii… - Journal of …, 2005 - journals.lww.com
Short-term infusion of carperitide (atrial natriuretic peptide) has beneficial effects on
neurohumoral factors; however, it remains unclear whether the effects are sustained for long …

Cardiorenal and neurohumoral effects of endogenous atrial natriuretic peptide in dogs with severe congestive heart failure using a specific antagonist for guanylate …

A Wada, T Tsutamoto, Y Matsuda, M Kinoshita - Circulation, 1994 - Am Heart Assoc
BACKGROUND To elucidate the extent of the compensatory role of endogenous atrial
natriuretic peptide (ANP) in severe congestive heart failure (CHF), we examined the …

α-Human atrial natriuretic peptide, carperitide, reduces infarct size but not arrhythmias after coronary occlusion/reperfusion in dogs

G Takagi, K Kiuchi, T Endo, T Yamamoto… - Journal of …, 2000 - journals.lww.com
Carperitide, a recombinant form of α-hANP, possesses potent diuretic, natriuretic, and
vasodilatory activity, and inhibits the renin-aldosterone system and sympathetic nervous …