Ultrasound-mediated drug delivery is a nonchemical, nonviral, and noninvasive method for
targeted transport of drugs and genes into cells. Molecules can be delivered into cells when …

Ultrasound has been shown to reversibly and irreversibly disrupt membranes of viable cells
through a mechanism believed to involve cavitation. Because cavitation is both temporally …

Purpose. To determine the dependence on acoustic parameters of molecular uptake and
viability of cells exposed to low-frequency ultrasound. Methods. DU145 prostate cancer cells …

Ultrasound (US) has been shown to transiently disrupt cell membranes and, thereby,
facilitate the loading of drugs and genes into viable cells. Because these effects are believed …

Application of ultrasound transiently permeabilizes cell membranes and offers a
nonchemical, nonviral, and noninvasive method for cellular drug delivery. Although the …

Ultrasound has been shown to deliver small compounds, macromolecules, and DNA into
cells, which suggests potential applications in drug and gene delivery. However, the effect of …

Using conditions different from conventional medical imaging or laboratory cell lysis,
ultrasound has recently been shown to reversibly increase plasma membrane permeability …

Purpose Ultrasound-induced cavitation facilitates cellular uptake of drugs via increased
membrane permeability. Here, the purpose was to evaluate the duration of enhanced …

Most applications of therapeutic ultrasound (US) for intracellular delivery of drugs, proteins,
DNA/RNA and other compounds would benefit from efficient uptake of these molecules into …

Applications of ultrasound for noninvasive drug and gene delivery have been limited by
associated cell death as a result of sonication. In this study, we sought to quantify the …