HR Guzman, DX Nguyen, S Khan… - The Journal of the …, 2001 - pubs.aip.org
Ultrasound has been shown to reversibly and irreversibly disrupt membranes of viable cells through a mechanism believed to involve cavitation. Because cavitation is both temporally …
K Keyhani, HR Guzmán, A Parsons, TN Lewis… - Pharmaceutical …, 2001 - Springer
Purpose. To determine the dependence on acoustic parameters of molecular uptake and viability of cells exposed to low-frequency ultrasound. Methods. DU145 prostate cancer cells …
SA Cochran, MR Prausnitz - Ultrasound in medicine & biology, 2001 - Elsevier
Ultrasound (US) has been shown to transiently disrupt cell membranes and, thereby, facilitate the loading of drugs and genes into viable cells. Because these effects are believed …
Application of ultrasound transiently permeabilizes cell membranes and offers a nonchemical, nonviral, and noninvasive method for cellular drug delivery. Although the …
HR Guzmán, DX Nguyen, AJ McNamara… - Journal of …, 2002 - Elsevier
Ultrasound has been shown to deliver small compounds, macromolecules, and DNA into cells, which suggests potential applications in drug and gene delivery. However, the effect of …
RK Schlicher, H Radhakrishna, TP Tolentino… - Ultrasound in medicine …, 2006 - Elsevier
Using conditions different from conventional medical imaging or laboratory cell lysis, ultrasound has recently been shown to reversibly increase plasma membrane permeability …
A Yudina, M Lepetit-Coiffé, CTW Moonen - Molecular imaging and biology, 2011 - Springer
Purpose Ultrasound-induced cavitation facilitates cellular uptake of drugs via increased membrane permeability. Here, the purpose was to evaluate the duration of enhanced …
Y Liu, J Yan, MR Prausnitz - Ultrasound in medicine & biology, 2012 - Elsevier
Most applications of therapeutic ultrasound (US) for intracellular delivery of drugs, proteins, DNA/RNA and other compounds would benefit from efficient uptake of these molecules into …
JD Hutcheson, RK Schlicher, HK Hicks… - Ultrasound in medicine & …, 2010 - Elsevier
Applications of ultrasound for noninvasive drug and gene delivery have been limited by associated cell death as a result of sonication. In this study, we sought to quantify the …