Plasma membrane poration induced by ultrasound exposure: implication for drug delivery

S Mehier-Humbert, T Bettinger, F Yan… - Journal of controlled …, 2005 - Elsevier
Sonoporation, in the presence of ultrasound contrast agents (UCA), is a technique that
permits the transfer of drugs, including genes, into cells. In this study, the size of the pores …

Effects of ultrasound on “solid” mammalian tissues and tumors in vivo

PP Lele - … : Medical Applications, Biological Effects, and Hazard …, 1987 - Springer
Over the last decade, the main thrust of research on bio-effects of ultrasound has been
directed towards prevention of the occurrence of any effects that may potentially be injurious …

Induction of cell-membrane porosity by ultrasound

K Tachibana, T Uchida, K Ogawa, N Yamashita… - The Lancet, 1999 - thelancet.com
within cells with acoustic energy. The cell-killing mechanism of these treatments has not
been clearly determined. To identify the site and degree of damage to tumour cells by …

Ultrasound-triggered drug targeting of tumors in vitro and in vivo

NY Rapoport, DA Christensen, HD Fain, L Barrows… - Ultrasonics, 2004 - Elsevier
The new modality of drug targeting of tumors that we are currently developing is based on
drug encapsulation in polymeric micelles, followed by the localized release at the tumor site …

[图书][B] Ultrasound: its applications in medicine and biology

FJ Fry - 2013 - books.google.com
Methods and Phenomena, 3: Ultrasound: Its Applications in Medicine and Biology, Part II
focuses on the applications of ultrasound in biology and medicine, including irradiation …

Changes in cell morphology due to plasma membrane wounding by acoustic cavitation

RK Schlicher, JD Hutcheson, H Radhakrishna… - Ultrasound in medicine …, 2010 - Elsevier
Acoustic cavitation-mediated wounding (ie, sonoporation) has great potential to improve
medical and laboratory applications requiring intracellular uptake of exogenous molecules; …

Ultrasound-enhanced drug delivery for cancer

S Mo, CC Coussios, L Seymour… - Expert opinion on drug …, 2012 - Taylor & Francis
Introduction: Ultrasound, which has traditionally been used as a diagnostic tool, is
increasingly being used in non-invasive therapy and drug delivery. Areas covered: Of …

The promise of sonodynamic therapy

M Trendowski - Cancer and Metastasis Reviews, 2014 - Springer
Sonodynamic therapy is a potential cancer treatment modality that has been gaining support
due to its effectiveness in both in vitro and in vivo studies. The therapeutic method combines …

Ultrasonic technologies in imaging and drug delivery

YJ Ho, CC Huang, CH Fan, HL Liu, CK Yeh - Cellular and Molecular Life …, 2021 - Springer
Ultrasonic technologies show great promise for diagnostic imaging and drug delivery in
theranostic applications. The development of functional and molecular ultrasound imaging is …

Ultrasonic exposure thresholds for changes in cells and tissues

CR Hill - The Journal of the Acoustical Society of America, 1972 - pubs.aip.org
The first part of this paper reports an experimental investigation of some parameters that
control the occurrence of biologically effective cavitation‐type phenomena in the frequency …