The development of cell polarity in Madin-Darby canine kidney (MDCK) cells has been
analyzed under conditions in which cells are induced to form multicellular epithelial cysts in …

ABSTRACT A fundamental aspect in the morphogenesis of a polarized epithelium is the
formation of structurally and functionally distinct apical and basal-lateral domains of the …

The time course of development of polarity of an apical (184-kD) and a basolateral (63-kD)
plasma membrane protein of Madin-Darby canine kidney cells was followed using …

The generation of cell surface polarity in transporting epithelial cells occurs in three distinct
stages that involve cell-cell recognition and adhesion, cell surface remodelling to form …

Organization of proteins into structurally and functionally distinct plasma membrane domains
is an essential characteristic of polarized epithelial cells. Based on studies with cultured …

The" Ca2+ switch" model with cultured Madin-Darby canine kidney (MDCK) cells is useful in
studying the biogenesis of epithelial polarity and junction formation and provides insight into …

The development of surface polarity has been studied in the epithelial Madin‐Darby canine
kidney (MDCK) cell line by examining two basolateral markers: a monoclonal antibody …

Studies of the developing trophectoderm in the mouse embryo have shown that extensive
cellular remodeling occurs during epithelial formation. In this investigation, confocal …

Epithelial cell polarity is essential for the establishment and maintenance of morphological
and functional asymmetries that underlie normal renal structure and function and are …

The role of extracellular matrix in the regulation of epithelial cell surface polarity
development was studied using MDCK cells. Previous work has demonstrated that MDCK …