The aryl hydrocarbon receptor (AhR) binds structurally diverse ligands that vary from the environmental toxicant 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) to AhR-active …
L Stejskalova, Z Dvorak, P Pavek - Current drug metabolism, 2011 - ingentaconnect.com
Aryl hydrocarbon receptor (AhR) is an important transcriptional regulator of drug metabolizing enzymes that dominantly controls the expression of cytochrome P450 CYP1 …
The arylhydrocarbon receptor (AhR) pathway is known to be critical for cellular events, especially for those evoked by several environmental chemicals such as 2, 3, 7, 8 …
L Lin, Y Dai, Y Xia - European Journal of Medicinal Chemistry, 2022 - Elsevier
The aryl hydrocarbon receptor (AhR), discovered 46 years ago, is a transcript factor member of the basic helix-loop-helix Per-ARNT-SIM (bHLH-PAS) family deeply implicated in health …
L Sládeková, S Mani, Z Dvořák - Biochemical Pharmacology, 2023 - Elsevier
The aryl hydrocarbon receptor (AhR) belongs to the essential helix-loop-helix transcription factors family. This receptor has a central role in determining host physiology and a variety of …
ÁC Roman, JM Carvajal-Gonzalez, JM Merino… - Pharmacology & …, 2018 - Elsevier
The aryl hydrocarbon receptor (AhR) is well-known for its major contributions to the cellular responses against environmental toxins and carcinogens. Notably, AhR has also emerged …
N Guerrina, H Traboulsi, DH Eidelman… - International journal of …, 2018 - mdpi.com
Much of what is known about the Aryl Hydrocarbon Receptor (AhR) centers on its ability to mediate the deleterious effects of the environmental toxicant 2, 3, 7, 8-tetrachlorodibenzo-p …
KW Bock, C Köhle - Biochemical pharmacology, 2006 - Elsevier
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and member of the bHLH/PAS (basic Helix-Loop-Helix/Per-Arnt-Sim) family of chemosensors and …