[HTML][HTML] The ecology of plasmid-coded antibiotic resistance: a basic framework for experimental research and modeling

M Zwanzig - Computational and Structural Biotechnology Journal, 2021 - Elsevier
Many antibiotic resistance genes are associated with plasmids. The ecological success of
these mobile genetic elements within microbial communities depends on varying …

The evolution of plasmid-carried antibiotic resistance

F Svara, DJ Rankin - BMC evolutionary biology, 2011 - Springer
Background Antibiotic resistance represents a significant public health problem. When
resistance genes are mobile, being carried on plasmids or phages, their spread can be …

Mathematical models of plasmid population dynamics

JCR Hernández-Beltrán, A San Millán… - Frontiers in …, 2021 - frontiersin.org
With plasmid-mediated antibiotic resistance thriving and threatening to become a serious
public health problem, it is paramount to increase our understanding of the forces that …

Evolutionary paths that expand plasmid host-range: implications for spread of antibiotic resistance

W Loftie-Eaton, H Yano, S Burleigh… - Molecular biology …, 2016 - academic.oup.com
Abstract The World Health Organization has declared the emergence of antibiotic resistance
to be a global threat to human health. Broad-host-range plasmids have a key role in causing …

[HTML][HTML] Current perspectives on the dynamics of antibiotic resistance in different reservoirs

M Caniça, V Manageiro, D Jones-Dias… - Research in …, 2015 - Elsevier
Antibiotic resistance consists of a dynamic web. In this review, we describe the path by
which different antibiotic residues and antibiotic resistance genes disseminate among …

Global epistasis in plasmid-mediated antimicrobial resistance

J DelaFuente, J Diaz-Colunga, A Sanchez… - Molecular systems …, 2024 - embopress.org
Antimicrobial resistance (AMR) in bacteria is a major public health threat and conjugative
plasmids play a key role in the dissemination of AMR genes among bacterial pathogens …

Simulating the influence of conjugative-plasmid kinetic values on the multilevel dynamics of antimicrobial resistance in a membrane computing model

M Campos, Á San Millán, JM Sempere… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Bacterial plasmids harboring antibiotic resistance genes are critical in the spread of
antibiotic resistance. It is known that plasmids differ in their kinetic values, ie, conjugation …

The spread of antibiotic resistance is driven by plasmids amongst the fastest evolving and of broadest host range

C Coluzzi, EPC Rocha - bioRxiv, 2024 - biorxiv.org
Microorganisms endure novel challenges for which other microorganisms in other biomes
may have already evolved solutions. This is the case of nosocomial bacteria under antibiotic …

Emerging patterns of plasmid-host coevolution that stabilize antibiotic resistance

T Stalder, LM Rogers, C Renfrow, H Yano, Z Smith… - Scientific reports, 2017 - nature.com
Multidrug resistant bacterial pathogens have become a serious global human health threat,
and conjugative plasmids are important drivers of the rapid spread of resistance to last …

Predicting how evolution will beat us

T Ellis - Microbial biotechnology, 2018 - pmc.ncbi.nlm.nih.gov
Predicting how evolution will beat us - PMC Skip to main content Here's how you know Official
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