Safety Profile of Molnupiravir with Significant Effect on COVID-19: A Review

T Mukherjee, P Mal, AK Upadhyay… - Current Drug …, 2023 - ingentaconnect.com
Background: As the COVID era unfolds, researchers reveal that rapid changes in viral
genetic material allow viruses to circumvent challenges triggered by the host immune …

[HTML][HTML] Effectiveness of molnupiravir in the treatment of patients with COVID-19: A Systematic Review and Meta-Analysis

M Zaboli Mahdiabadi, C Karami, E Saber… - Studies in Medical …, 2023 - umj.umsu.ac.ir
Background & Aims: Molnupiravir is an oral antiviral drug which is used in the treatment of
patients with COVID-19. The purpose of this study was to investigate the effectiveness and …

Will Molnupiravir be the First Oral Treatment for High-Risk Non-Hospitalized Patients with Mild-Moderate COVID-19?

S Rao, M Singh - DHR Proceedings, 2021 - dhrproceedings.org
The first case of SARS-CoV-2 infection in United States was confirmed on January 19, 2020,
in a man who had returned home to Snohomish County, Washington on January 15, 2020 …

Real-world effectiveness of molnupiravir and nirmatrelvir/ritonavir as treatments for COVID-19 in patients at high risk

D Paraskevis, M Gkova, K Mellou… - The Journal of …, 2023 - academic.oup.com
Background Using a retrospective cohort study design, we aimed to evaluate the
effectiveness of molnupiravir and nirmatrelvir/ritonavir in patients with SARS-CoV-2 who …

Impact of molnupiravir treatment on patient-reported COVID-19 symptoms in the phase 3 MOVe-OUT trial: a randomized, placebo-controlled trial

Y Guan, A Puenpatom, MG Johnson… - Clinical Infectious …, 2023 - academic.oup.com
Background Molnupiravir is an orally administered antiviral authorized for COVID-19
treatment in adults at high risk of progression to severe disease. Here, we report secondary …

Molnupiravir and risk of hospital admission or death in adults with covid-19: emulation of a randomized target trial using electronic health records

Y Xie, B Bowe, Z Al-Aly - bmj, 2023 - bmj.com
Objective To emulate a randomized target trial to estimate the association between the
antiviral drug molnupiravir and hospital admission or death in adults with SARS-CoV-2 …

Molnupiravir and risk of post-acute sequelae of covid-19: cohort study

Y Xie, T Choi, Z Al-Aly - bmj, 2023 - bmj.com
Objective To examine whether treatment with the antiviral agent molnupiravir during the first
five days of SARS-CoV-2 infection is associated with reduced risk of post-acute adverse …

[HTML][HTML] Safety profile of molnupiravir in the treatment of COVID-19: A descriptive study based on FAERS data

G Santi Laurini, N Montanaro, D Motola - Journal of Clinical Medicine, 2022 - mdpi.com
Concerns have been raised about the actual benefit and safety of molnupiravir, a new
antiviral treatment for coronavirus disease 2019 (COVID-19). In order to provide additional …

Human safety, tolerability, and pharmacokinetics of a novel broad-spectrum oral antiviral compound, molnupiravir, with activity against SARS-CoV-2

WP Painter, W Holman, JA Bush, F Almazedi, H Malik… - medrxiv, 2020 - medrxiv.org
Abstract Molnupiravir, EIDD-2801/MK-4482, the prodrug of the ribonucleoside analog ß-d-
N4-hydroxycytidine (NHC), has activity against a number of RNA viruses including severe …

Molnupiravir: evidence by press release

JA Cave, D Phizackerley - Drug and Therapeutics Bulletin, 2022 - dtb.bmj.com
On 4 November 2021, the Medicines and Healthcare products Regulatory Agency (MHRA)
announced that it had approved molnupiravir (▼ Lagevrio) as the first oral antiviral drug …