Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody
Z Lv, YQ Deng, Q Ye, L Cao, CY Sun, C Fan, W Huang… - Science, 2020 - science.org
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health …
syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health …
A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2
X Chi, R Yan, J Zhang, G Zhang, Y Zhang, M Hao… - Science, 2020 - science.org
Developing therapeutics against severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) could be guided by the distribution of epitopes, not only on the receptor binding …
CoV-2) could be guided by the distribution of epitopes, not only on the receptor binding …
[HTML][HTML] Humanized single domain antibodies neutralize SARS-CoV-2 by targeting the spike receptor binding domain
X Chi, X Liu, C Wang, X Zhang, X Li, J Hou… - Nature …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads worldwide and
leads to an unprecedented medical burden and lives lost. Neutralizing antibodies provide …
leads to an unprecedented medical burden and lives lost. Neutralizing antibodies provide …
[HTML][HTML] Development and structural basis of a two-MAb cocktail for treating SARS-CoV-2 infections
The ongoing pandemic of coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Neutralizing antibodies against SARS …
respiratory syndrome coronavirus 2 (SARS-CoV-2). Neutralizing antibodies against SARS …
[HTML][HTML] A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein
Vaccines and therapeutics are urgently needed for the pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we screen human monoclonal …
respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we screen human monoclonal …
[HTML][HTML] A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes
Y Guo, L Huang, G Zhang, Y Yao, H Zhou… - Nature …, 2021 - nature.com
COVID-19 pandemic caused by SARS-CoV-2 constitutes a global public health crisis with
enormous economic consequences. Monoclonal antibodies against SARS-CoV-2 can …
enormous economic consequences. Monoclonal antibodies against SARS-CoV-2 can …
[HTML][HTML] Structural analysis of neutralizing epitopes of the SARS-CoV-2 spike to guide therapy and vaccine design strategies
MT Finkelstein, AG Mermelstein, E Parker Miller… - Viruses, 2021 - mdpi.com
Coronavirus research has gained tremendous attention because of the COVID-19
pandemic, caused by the novel severe acute respiratory syndrome coronavirus (nCoV or …
pandemic, caused by the novel severe acute respiratory syndrome coronavirus (nCoV or …
[HTML][HTML] A potently neutralizing antibody protects mice against SARS-CoV-2 infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for millions
of infections and hundreds of thousands of deaths globally. There are no widely available …
of infections and hundreds of thousands of deaths globally. There are no widely available …
[HTML][HTML] Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies
Immediately from the outset of the COVID-19 pandemic, researchers from diverse
biomedical and biological disciplines have united to study the novel pandemic virus, SARS …
biomedical and biological disciplines have united to study the novel pandemic virus, SARS …
Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
PJM Brouwer, TG Caniels, K van der Straten… - Science, 2020 - science.org
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
had a large impact on global health, travel, and economy. Therefore, preventative and …
had a large impact on global health, travel, and economy. Therefore, preventative and …