Despite medical and technological advances to contain the proliferation of pancreatic
cancer, many diagnoses are late due to the high specificity of this type of cancer. Because it …

Pancreatic cancer is an aggressive disease with a high death rate and is difficult to treat.
This disease, in the most cases, is asymptomatic until it progresses to an advanced stage …

Background Cancer is a significant public health problem worldwide and constitutes the
second leading cause of death after cardiovascular disease. This study was thus designed …

In one-pot strategy, diazotization of methyl anthranilate 5 followed by addition of amino acid
ester hydrochloride, we have prepared methyl-2-(4-oxobenzotriazin-3 (4 H)-yl) alkanoates …

Background: Natural products from herbs are abundant and display powerful anti-cancer
activities. Objectives: In the current study, B-Raf kinase protein (PDB: 3OG7), a potent target …

Several studies have linked Cancer stem cells (CSCs) to cancer resistance development to
chemotherapy and radiotherapy. ALDH1A1 is a key enzyme that regulates the gene …

Cancer is defined as a disease caused by progressive and abnormal cell proliferation in the
body. This condition is caused by deoxyribonucleic acid (DNA) changes, which causes cells …

Background: Protoberberine isoquinoline alkaloids are found in many plant species. They
consist of a diverse class of secondary metabolites with many pharmacologically active …

VEGFR-2 is a significant target in cancer treatment, inhibiting angiogenesis and impeding
tumor growth. Utilizing the essential pharmacophoric structural properties, a new semi …

We have semi-synthesized a natural product 7-acetylhorminone from crude extract of
Premna obtusifolia (Indian headache tree), which is active against colorectal cancer after …