We recently reported on a new class of branched amphiphilic peptides that associate with
double stranded DNA and promote in vitro transfection of eukaryotic cells. In the present …

Over the past decade, peptides have emerged as a new family of potential carriers in gene
therapy. Peptides are easy to synthesize and quite stable. Additionally, sequences shared …

Branched amphipathic peptide capsules (BAPCs) are biologically derived, bilayer delimited,
nanovesicles capable of being coated by or encapsulating a wide variety of solutes. The …

Cationic oligopeptides fabricated from natural amino acids have been widely explored as
nonviral vectors for gene delivery, due to their biodegradability, greater biocompatibility …

In this study, two types of BolA‐like amphiphilic peptides with dual ligands comprising a
tumor‐targeting moiety of RGD sequence and a cell‐penetrating moiety of R8 sequence are …

To overcome the low efficiency and cytotoxicity associated with most non-viral DNA delivery
systems we developed a purely peptidic self-assembling system that is able to entrap single …

A small library of carriers consisting of various combinations of the cell penetrating peptide
TAT, the SV40 Large T protein nuclear localisation signal (NLS) and a cationic dendrimer of …

Amphipathic peptides constitute a class of molecules with the potential to develop as
efficient and safer alternatives to viral and other nonviral vectors for intracellular delivery of …

Nonviral vectors for gene therapy are a safer alternative to viral vectors that elicit a harmful
immune response. Artificial viruses combine the strengths of viral and nonviral vectors and …

Self‐assembled, biodegradable materials that embed fragile, soluble, or insoluble
compounds of therapeutic interest have potential use as drug delivery systems. The bead …