Acute lung injury (ALI) leading to acute respiratory distress syndrome is the major cause of
COVID-19 lethality. Cell entry of SARS-CoV-2 occurs via the interaction between its surface …

The spike protein of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can
interact with endothelial cells. However, no studies demonstrated the direct effect of the …

Currently, the world is suffering from the pandemic of coronavirus disease 2019 (COVID-19),
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that uses …

The coronavirus disease 2019 (COVID-19) pandemic began in January 2020 in Wuhan,
China, with a new coronavirus designated SARS-CoV-2. The principal cause of death from …

Abstract COVID-19, caused by SARS-CoV-2, is a respiratory disease associated with
inflammation and endotheliitis. Mechanisms underling inflammatory processes are unclear …

SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection relies on the
binding of S protein (Spike glycoprotein) to ACE (angiotensinconverting enzyme) 2 in the …

Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now spread globally. Some …

SARS-CoV-2 virus causes upper and lower respiratory diseases including pneumonia, and
in some cases, leads to lethal pulmonary failure. Angiotensin converting enzyme-2 (ACE2) …

Background. Emerging evidences suggest that in severe COVID-19, multi-organ failure is
associated with a hyperinflammatory state (the so-called “cytokine storm”) in combination …

The pathogenesis of COVID-19 is associated with a hyperinflammatory response; however,
the precise mechanism of SARS-CoV-2-induced inflammation is poorly understood. Here …