[PDF][PDF] Fluorescence imaging of influenza H1N1 mRNA in living infected cells using single‐chromophore FIT‐PNA

S Kummer, A Knoll, E Socher, L Bethge… - Angewandte Chemie …, 2011 - academia.edu
In light of the increasing importance assigned to RNA, significant efforts have been devoted
to the development of fluorescent oligonucleotide probes that allow the imaging of RNA …

PNA FIT-probes for the dual color imaging of two viral mRNA targets in influenza H1N1 infected live cells

S Kummer, A Knoll, E Socher, L Bethge… - Bioconjugate …, 2012 - ACS Publications
Fluorogenic hybridization probes that allow RNA imaging provide information as to how the
synthesis and transport of particular RNA molecules is orchestrated in living cells. In this …

A multicolor nanoprobe for detection and imaging of tumor‐related mRNAs in living cells

N Li, C Chang, W Pan, B Tang - … Chemie International Edition, 2012 - Wiley Online Library
Cancer is a leading cause of death worldwide and accounts for several millions of deaths
every year.[1] The survival of cancer patients is strongly associated with the stage of the …

DNA stains as surrogate nucleobases in fluorogenic hybridization probes

F Hövelmann, O Seitz - Accounts of chemical research, 2016 - ACS Publications
Conspectus The increasing importance assigned to RNA dynamics in cells and tissues calls
for probe molecules that enable fluorescence microscopy imaging in live cells. To achieve …

Dual fluorophore PNA FIT-probes− extremely responsive and bright hybridization probes for the sensitive detection of DNA and RNA

E Socher, A Knoll, O Seitz - Organic & biomolecular chemistry, 2012 - pubs.rsc.org
Fluorescently labeled oligonucleotides are commonly employed as probes to detect specific
DNA or RNA sequences in homogeneous solution. Useful probes should experience strong …

Fluorescence sensing of the panhandle structure of the influenza a virus RNA promoter by thiazole orange base surrogate-carrying peptide nucleic acid conjugated …

Y Sato, H Miura, T Tanabe, CU Okeke… - Analytical …, 2022 - ACS Publications
We have developed a new class of triplex-forming peptide nucleic acid (PNA)-based
fluorogenic probes for sensing of the panhandle structure of the influenza A virus (IAV) RNA …

LNA-enhanced DNA FIT-probes for multicolour RNA imaging

F Hövelmann, I Gaspar, J Chamiolo, M Kasper… - Chemical …, 2016 - pubs.rsc.org
The simultaneous imaging of different RNA molecules in homogeneous solution is a
challenge and requires optimisation to enable unambiguous staining of intracellular RNA …

Fluorogenic PNA probes

T Vilaivan - Beilstein Journal of Organic Chemistry, 2018 - beilstein-journals.org
Fluorogenic oligonucleotide probes that can produce a change in fluorescence signal upon
binding to specific biomolecular targets, including nucleic acids as well as non-nucleic acid …

A Color‐Shifting Near‐Infrared Fluorescent Aptamer–Fluorophore Module for Live‐Cell RNA Imaging

J Zhang, L Wang, A Jäschke, M Sunbul - Angewandte Chemie, 2021 - Wiley Online Library
Fluorescent light‐up RNA aptamers (FLAPs) have become promising tools for visualizing
RNAs in living cells. Specific binding of FLAPs to their non‐fluorescent cognate ligands …

[PDF][PDF] Tetramolecular fluorescence complementation for detection of specific RNAs in vitro

SJ Kellermann, AK Rath, A Rentmeister - ChemBioChem, 2013 - ziel.uni-luebeck.de
Asymmetrically localized RNA has been found in many cell types and organisms and
contributes to important developmental processes, such as mating type switching in yeast,[1] …