Gut microbiota and inflammatory bowel disease

L Chen, J Wang - WIREs Mechanisms of Disease, 2022 - Wiley Online Library
Gut microbiota refers to the complex aggregation of microbes in gut, including bacteria,
archaea, fungi, and viruses, and they exert marked influence on the host's health …

Gut dysbiosis in irritable bowel syndrome: a narrative review on correlation with disease subtypes and novel therapeutic implications

M Napolitano, E Fasulo, F Ungaro, L Massimino… - Microorganisms, 2023 - mdpi.com
Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder
characterized by chronic abdominal pain and altered bowel habits. It can be subclassified in …

The role of the gut microbiota in the treatment of inflammatory bowel diseases

I Aggeletopoulou, C Konstantakis… - Microbial …, 2019 - Elsevier
The human intestinal microbiota coevolves with its host through a symbiotic relationship and
exerts great influence on substantial functions including aspects of physiology, metabolism …

The metabolic nature of inflammatory bowel diseases

TE Adolph, M Meyer, J Schwärzler, L Mayr… - Nature Reviews …, 2022 - nature.com
Crohn's disease and ulcerative colitis, phenotypically comprising a spectrum of inflammatory
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …

Gut microbiota-derived metabolites in irritable bowel syndrome

L Xiao, Q Liu, M Luo, L Xiong - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Irritable bowel syndrome (IBS) is the most common functional bowel disorder worldwide and
is associated with visceral hypersensitivity, gut motility, immunomodulation, gut microbiota …

evidence for the role of gut microbiota in irritable bowel syndrome and its potential influence on therapeutic targets

HL Dupont - Alimentary pharmacology & therapeutics, 2014 - Wiley Online Library
Background Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disease with a
substantial social and economic burden. Treatment options remain limited and research on …

Novel mechanisms and clinical trial endpoints in intestinal fibrosis

J Wang, S Lin, JM Brown, D van Wagoner… - Immunological …, 2021 - Wiley Online Library
The incidence of inflammatory bowel diseases (IBD) worldwide has resulted in a global
public health challenge. Intestinal fibrosis leading to stricture formation and bowel …

The role of inflammation in irritable bowel syndrome (IBS)

QX Ng, AYS Soh, W Loke, DY Lim… - Journal of inflammation …, 2018 - Taylor & Francis
Irritable bowel syndrome (IBS) is a complex, functional gastrointestinal disorder
characterized by chronic abdominal pain or discomfort and altered bowel habits. Despite the …

Microbiome and its role in irritable bowel syndrome

M Pimentel, A Lembo - Digestive diseases and sciences, 2020 - Springer
Irritable bowel syndrome (IBS) is an extremely common and often very debilitating chronic
functional gastrointestinal disorder. Despite its prevalence, significant associated healthcare …

A cross talk between dysbiosis and gut-associated immune system governs the development of inflammatory arthropathies

A Kalinkovich, G Livshits - Seminars in Arthritis and Rheumatism, 2019 - Elsevier
Background Emerging evidence suggests that dysbiosis, imbalanced gut microbial
community, might be a key player in the development of various diseases, including …