Because they are obligate intracellular parasites, all viruses are exclusively and intimately
dependent upon host cells for replication. Viruses, in turn, induce profound changes within …

We studied the dynamics of the proteome of influenza virus A/PR/8/34 (H1N1) infected
Madin-Darby canine kidney cells up to 12 hours post infection by mass spectrometry based …

Influenza A virus exerts a large health burden during both yearly epidemics and global
pandemics. However, designing effective vaccine and treatment options has proven difficult …

Background To understand the molecular mechanism of host responses to highly
pathogenic avian influenza virus infection and to get an insight into the means through …

Recent outbreaks of avian influenza in humans have stressed the need for an improved
nonhuman primate model of influenza pathogenesis. In order to further develop a macaque …

Influenza A virus is one of the world's major uncontrolled pathogens, causing seasonal
epidemics as well as global pandemics. This was evidenced by the recent emergence and …

Over the last years virus–host cell interactions were investigated in numerous studies. Viral
strategies for evasion of innate immune response, inhibition of cellular protein synthesis and …

Virions are thought to contain all the essential proteins that govern virus egress from the host
cell and initiation of replication in the target cell. It has been known for some time that …

The host proteome response and molecular mechanisms that drive disease in vivo during
infection by a human isolate of the highly pathogenic avian influenza virus (HPAI) and 1918 …

To understand more fully the molecular events associated with highly virulent or attenuated
influenza virus infections, we have studied the effects of expression of the 1918 …