[HTML][HTML] Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis …
Cannabis is the most widely produced and consumed illicit psychoactive substance
worldwide. Occasional cannabis use can progress to frequent use, abuse and dependence …
worldwide. Occasional cannabis use can progress to frequent use, abuse and dependence …
GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability
Cannabis use is a heritable trait that has been associated with adverse mental health
outcomes. In the largest genome-wide association study (GWAS) for lifetime cannabis use to …
outcomes. In the largest genome-wide association study (GWAS) for lifetime cannabis use to …
Genome-wide association study identifies a novel locus for cannabis dependence
Despite moderate heritability, only one study has identified genome-wide significant loci for
cannabis-related phenotypes. We conducted meta-analyses of genome-wide association …
cannabis-related phenotypes. We conducted meta-analyses of genome-wide association …
[HTML][HTML] A large-scale genome-wide association study meta-analysis of cannabis use disorder
Background Variation in liability to cannabis use disorder has a strong genetic component
(estimated twin and family heritability about 50–70%) and is associated with negative …
(estimated twin and family heritability about 50–70%) and is associated with negative …
The genetic aetiology of cannabis use initiation: a meta‐analysis of genome‐wide association studies and a SNP‐based heritability estimation
While initiation of cannabis use is around 40% heritable, not much is known about the
underlying genetic aetiology. Here, we meta‐analysed two genome‐wide association …
underlying genetic aetiology. Here, we meta‐analysed two genome‐wide association …
[HTML][HTML] Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications
As recreational use of cannabis is being decriminalized in many places and medical use
widely sanctioned, there are growing concerns about increases in cannabis use disorder …
widely sanctioned, there are growing concerns about increases in cannabis use disorder …
Genome-wide association study of cannabis dependence severity, novel risk variants, and shared genetic risks
Importance Cannabis dependence (CAD) is a serious problem worldwide and is of growing
importance in the United States because cannabis is increasingly available legally …
importance in the United States because cannabis is increasingly available legally …
Cannabis controversies: how genetics can inform the study of comorbidity
A Agrawal, MT Lynskey - Addiction, 2014 - Wiley Online Library
Aims To review three key and controversial comorbidities of cannabis use—other illicit drug
use, psychosis and depression, as well as suicide, from a genetically informed perspective …
use, psychosis and depression, as well as suicide, from a genetically informed perspective …
Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality
M Soler Artigas, C Sánchez-Mora, P Rovira… - Molecular …, 2020 - nature.com
Attention-deficit/hyperactivity disorder (ADHD) is a severely impairing neurodevelopmental
disorder with a prevalence of 5% in children and adolescents and of 2.5% in adults …
disorder with a prevalence of 5% in children and adolescents and of 2.5% in adults …
Cannabis use, depression and self‐harm: phenotypic and genetic relationships
Abstract Background and Aims The use of cannabis has previously been linked to both
depression and self‐harm; however, the role of genetics in this relationship is unclear. This …
depression and self‐harm; however, the role of genetics in this relationship is unclear. This …