Dorsal tegmental dopamine neurons gate associative learning of fear

F Groessl, T Munsch, S Meis, J Griessner… - Nature …, 2018 - nature.com
Functional neuroanatomy of Pavlovian fear has identified neuronal circuits and synapses
associating conditioned stimuli with aversive events. Hebbian plasticity within these …

Placing prediction into the fear circuit

GP McNally, JP Johansen, HT Blair - Trends in neurosciences, 2011 - cell.com
Pavlovian fear conditioning depends on synaptic plasticity at amygdala neurons. Here, we
review recent electrophysiological, molecular and behavioral evidence suggesting the …

A dopaminergic switch for fear to safety transitions

R Luo, A Uematsu, A Weitemier, L Aquili… - Nature …, 2018 - nature.com
Overcoming aversive emotional memories requires neural systems that detect when fear
responses are no longer appropriate so that they can be extinguished. The midbrain ventral …

A VTA to basal amygdala dopamine projection contributes to signal salient somatosensory events during fear learning

W Tang, O Kochubey, M Kintscher… - Journal of …, 2020 - Soc Neuroscience
The amygdala is a brain area critical for the formation of fear memories. However, the nature
of the teaching signal (s) that drive plasticity in the amygdala are still under debate. Here, we …

Bidirectional control of fear memories by cerebellar neurons projecting to the ventrolateral periaqueductal grey

JL Frontera, H Baba Aissa, RW Sala… - Nature …, 2020 - nature.com
Fear conditioning is a form of associative learning that is known to involve different brain
areas, notably the amygdala, the prefrontal cortex and the periaqueductal grey (PAG). Here …

A feedback neural circuit for calibrating aversive memory strength

T Ozawa, EA Ycu, A Kumar, LF Yeh, T Ahmed… - Nature …, 2017 - nature.com
Aversive experiences powerfully regulate memory formation, and memory strength is
proportional to the intensity of these experiences. Inhibition of the neural circuits that convey …

Dendritic inhibition in the hippocampus supports fear learning

M Lovett-Barron, P Kaifosh, MA Kheirbek, N Danielson… - Science, 2014 - science.org
Fear memories guide adaptive behavior in contexts associated with aversive events. The
hippocampus forms a neural representation of the context that predicts aversive events …

An organization of visual and auditory fear conditioning in the lateral amygdala

HC Bergstrom, LR Johnson - Neurobiology of learning and memory, 2014 - Elsevier
Pavlovian fear conditioning is an evolutionary conserved and extensively studied form of
associative learning and memory. In mammals, the lateral amygdala (LA) is an essential …

New vistas on amygdala networks in conditioned fear

D Paré, GJ Quirk, JE Ledoux - Journal of neurophysiology, 2004 - journals.physiology.org
It is currently believed that the acquisition of classically conditioned fear involves
potentiation of conditioned thalamic inputs in the lateral amygdala (LA). In turn, LA cells …

Rethinking the fear circuit: the central nucleus of the amygdala is required for the acquisition, consolidation, and expression of Pavlovian fear conditioning

AE Wilensky, GE Schafe, MP Kristensen… - Journal of …, 2006 - Soc Neuroscience
In the standard model of pavlovian fear learning, sensory input from neutral and aversive
stimuli converge in the lateral nucleus of the amygdala (LA), in which alterations in synaptic …