Hepatocellular carcinogenesis is attributed to the reprogramming of cellular metabolism as a
consequence of the alteration in metabolite-related gene regulation. Identifying the …

During the cancerous transformation of normal hepatocytes into hepatocellular carcinoma
(HCC), the enzyme catalyzing the first rate-limiting step of glycolysis, namely the …

Hepatocellular carcinoma (HCC) is a tumor that exhibits glucometabolic reprogramming,
with a high incidence and poor prognosis. Usually, HCC is not discovered until an advanced …

Cancer cells sustain high levels of glycolysis and glutaminolysis via reprogramming of
intracellular metabolism, which represents a driver of hepatocellular carcinoma (HCC) …

HCC (Hepatocellular carcinoma) cells exhibit greater metabolic plasticity than normal
hepatocytes since they must survive in a dynamic microenvironment where nutrients and …

Hepatocellular carcinoma (HCC) cells rapidly switch their energy source from oxidative
phosphorylation to glycolytic metabolism in order to efficiently proliferate. However, the …

Emerging studies have suggested that the Hippo pathway is involved in the tumorigenesis of
hepatocellular carcinoma (HCC). However, the key regulator of the Hippo pathway in liver …

Notwithstanding the numerous drugs available for liver cancer, emerging evidence suggests
that chemotherapeutic resistance is a significant issue. HGF and its receptor MET play …

Metabolic reprogramming is a hallmark of cancer, including hepatocellular carcinoma
(HCC). However, its role in HCC remains to be elucidated. Herein, we identified GTP …

Background Hepatocellular carcinoma (HCC) cells undergo reprogramming of glucose
metabolism to support uncontrolled proliferation, of which the intrinsic mechanism still merits …