Clinical significance of measuring serum cytokine levels as inflammatory biomarkers in adult and pediatric COVID-19 cases: A review

BM Liu, TB Martins, LK Peterson, HR Hill - Cytokine, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a rapidly evolving infectious/inflammatory
disorder which has turned into a global pandemic. With severe acute respiratory syndrome …

[HTML][HTML] Serial measurement of cytokines strongly predict COVID-19 outcome

HS Ozger, R Karakus, EN Kuscu, UE Bagriacik… - PloS one, 2021 - journals.plos.org
Purpose Cytokines are major mediators of COVID-19 pathogenesis and several of them are
already being regarded as predictive markers for the clinical course and outcome of COVID …

Predictive value of cytokine/chemokine responses for the disease severity and management in children and adult cases with COVID‐19

Y Ozsurekci, K Aykac, AG Er, B Halacli… - Journal of medical …, 2021 - Wiley Online Library
The disease course of children with coronavirus disease 2019 (COVID‐19) seems milder as
compared with adults, however, actual reason of the pathogenesis still remains unclear …

[HTML][HTML] High levels of pro-inflammatory SARS-CoV-2-specific biomarkers revealed by in vitro whole blood cytokine release assay (CRA) in recovered and long …

SMR Gomes, ACS Brito, WFP Manfro, M Ribeiro-Alves… - Plos one, 2023 - journals.plos.org
Background Cytokines induced by SARS-CoV-2 infection play a crucial role in the
pathophysiology of COVID-19 and hyperinflammatory responses have been associated with …

[HTML][HTML] A deep look into COVID-19 severity through dynamic changes in blood cytokine levels

DA Kleymenov, EN Bykonia, LI Popova… - Frontiers in …, 2021 - frontiersin.org
An excessive inflammatory response to SARS-CoV-2 is thought to be a major cause of
disease severity and mortality in patients with COVID-19. Longitudinal analysis of cytokine …

[HTML][HTML] Cytokine signature and COVID-19 prediction models in the two waves of pandemics

S Cabaro, V D'Esposito, T Di Matola, S Sale… - Scientific Reports, 2021 - nature.com
In Europe, multiple waves of infections with SARS-CoV-2 (COVID-19) have been observed.
Here, we have investigated whether common patterns of cytokines could be detected in …

[HTML][HTML] Temporal profiling of plasma cytokines, chemokines and growth factors from mild, severe and fatal COVID-19 patients

ZS Xu, T Shu, L Kang, D Wu, X Zhou, BW Liao… - Signal transduction and …, 2020 - nature.com
In December 2019, a novel coronavirus that is related to severe acute respiratory syndrome
coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) in …

[HTML][HTML] Cytokine signature associated with disease severity in COVID-19

J Guo, S Wang, H Xia, D Shi, Y Chen, S Zheng… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) broke out and then became a global epidemic at the
end of 2019. With the increasing number of deaths, early identification of disease severity …

Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

H Han, Q Ma, C Li, R Liu, L Zhao, W Wang… - Emerging microbes & …, 2020 - Taylor & Francis
Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly
spread across many other countries. While the majority of patients were considered mild …

[PDF][PDF] Elevated plasma levels of selective cytokines in COVID-19 patients reflect viral load and lung injury

Y Liu, C Zhang, F Huang, Y Yang, F Wang… - National Science …, 2020 - academic.oup.com
A recent outbreak of pneumonia in Wuhan, China was found to be caused by a 2019 novel
coronavirus (2019-nCoV or SARS-CoV-2 or HCoV-19). We previously reported the clinical …