[HTML][HTML] Nirmatrelvir/ritonavir prescription rate and outcomes in coronavirus disease 2019: a single center study

JJ Park, J Lee, YB Seo, SH Na - Infection & Chemotherapy, 2022 - ncbi.nlm.nih.gov
Background Nirmatrelvir/ritonavir was Korea's first oral antiviral agent to treat coronavirus
disease 2019 (COVID-19). We analyzed the nirmatrelvir/ritonavir prescription rate and …

Nirmatrelvir/ritonavir for the treatment of immunocompromised adult patients with early‐stage symptomatic COVID‐19: A real‐life experience

JM Caso, M Fernández‐Ruiz… - Journal of Medical …, 2023 - Wiley Online Library
Regardless of vaccination status, progression to severe coronavirus disease 2019 (COVID‐
19) is still a relevant cause of morbidity among immunocompromised patients. Despite the …

[HTML][HTML] Antiviral drug treatment for nonsevere COVID-19: a systematic review and network meta-analysis

T Pitre, R Van Alstine, G Chick, G Leung, D Mikhail… - Cmaj, 2022 - Can Med Assoc
Background: Randomized trial evidence suggests that some antiviral drugs are effective in
patients with COVID-19. However, the comparative effectiveness of antiviral drugs in …

Clinical outcomes following treatment for COVID-19 with nirmatrelvir/ritonavir and molnupiravir among patients living in nursing homes

BHM Ma, TCF Yip, GCY Lui, MSM Lai, E Hui… - JAMA Network …, 2023 - jamanetwork.com
Importance Older patients living in nursing homes are at very high risk of mortality after
getting COVID-19. Objective To evaluate outcomes following oral antiviral treatment for …

Impact of the use of oral antiviral agents on the risk of hospitalization in community coronavirus disease 2019 patients (COVID-19)

TCF Yip, GCY Lui, MSM Lai, VWS Wong… - Clinical infectious …, 2023 - academic.oup.com
Background We examined the effectiveness of molnupiravir and nirmatrelvir/ritonavir in
reducing hospitalization and deaths in a real-world cohort of nonhospitalized patients with …

[HTML][HTML] Favipiravir versus arbidol for clinical recovery rate in moderate and severe adult COVID-19 patients: a prospective, multicenter, open-label, randomized …

C Chen, Y Zhang, J Huang, P Yin, Z Cheng… - Frontiers in …, 2021 - frontiersin.org
Background: In addition to supportive therapy, antiviral therapy is an effective treatment for
coronavirus disease 2019 (COVID-19). Objective: To compare the efficacy and safety of …

[HTML][HTML] Effectiveness of nirmatrelvir-ritonavir for the treatment of patients with mild to moderate COVID-19 and at high risk of hospitalization: systematic review and …

KM Souza, G Carrasco, R Rojas-Cortés… - Plos one, 2023 - journals.plos.org
Objective To assess the effectiveness of nirmatrelvir-ritonavir in the treatment of outpatients
with mild to moderate COVID-19 who are at higher risk of developing severe illness, through …

Small-molecule anti-COVID-19 drugs and a focus on China's homegrown mindeudesivir (VV116)

Q Cao, Y Ding, Y Xu, M Li, R Zheng, Z Cao, W Wang… - Frontiers of …, 2024 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic agents that target severe acute respiratory syndrome …

[HTML][HTML] First-generation oral antivirals against SARS-CoV-2

P Sendi, RR Razonable, SB Nelson, A Soriano… - Clinical Microbiology …, 2022 - Elsevier
Background Oral drugs against severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) have received emergency use authorization for the treatment of mild-to-moderate …

[HTML][HTML] The antiviral effect of nirmatrelvir/ritonavir during COVID-19 pandemic real-world data

V Petrakis, P Rafailidis, G Trypsianis, D Papazoglou… - Viruses, 2023 - mdpi.com
Introduction: Vaccination against SARS-CoV-2 and the prevalence of Omicron variants have
reduced the risk of the severe clinical progress of COVID-19. However, the risk of …