In this study, intracellular pH-responsive nanoparticles (NPs) of hyaluronic acid-hydrazone
linkage-doxorubicin (HA-hyd-DOX) were designed and prepared for acid-triggered release …

Hyaluronic acid (HA)-based doxorubicin (DOX) nanoparticles (HA-NPs) were fabricated via
ion-pairing between positively charged DOX and negatively charged HA, which displayed …

Hyaluronic acid (HA) is being actively studied as a drug carrier due to its favorable
properties and functional groups for chemical modification. Despite its high functionality, p K …

In recent years, biomacromolecules have been widely used in anti-tumor delivery systems
due to the biocompatibility and biodegradability. However, their applications are limited due …

A novel GHH copolymer was synthesized using hyaluronic acid modified with glycyrrhetinic
acid and L‑histidine (His), and doxorubicin‑loaded GHH nanoparticles (DOX/GHH) were …

The nanoparticulate drug delivery systems (NDDS) demonstrate a relatively ideal
therapeutic efficacy during cancer therapy Regarding the high tumor-target capacity and …

Herein, we describe the preparation of a targeted cellular delivery system for morin hydrate
(MH), based on a low-molecular-weight hyaluronic acid-poly (butyl cyanoacrylate)(HA …

In this study, we report the development of a novel pH-responsive nanoparticle composed of
hyaluronic acid (HA) grafted with functional 3-diethylaminopropyl (DEAP) groups (HA-g …

Biocompatible nanogels were prepared using thiol modified hyaluronic acid and diacrylated
pluronic F127 polymer. A simple Michael type addition reaction of activated thiol groups on …

Hyaluronic acid (HA) has been widely investigated in cancer therapy due to its excellent
characteristics. HA, which is a linear anionic polymer, has biocompatibility, biodegradability …