Objectives: Cannabidiol (CBD) is hypothesized as a potential treatment for opioid addiction,
with safety studies an important first step for medication development. We determined CBD …

Background: Cannabidiol is being pursued as a therapeutic treatment for multiple
conditions, usually by oral delivery. Animal studies suggest oral bioavailability is low, but …

Background A formal single ascending and multiple dose pharmacokinetic (PK) trial of
cannabidiol (CBD) oral solution was required to determine the safety and tolerability of CBD …

Aims Cannabidiol (CBD) is a cannabis‐derived medicinal product with potential application
in a wide‐variety of contexts; however, its effective dose in different disease states remains …

Background There is increasing interest in the use of purified cannabidiol (CBD) as a
treatment for a wide range of conditions due to its reported anti-inflammatory, anxiolytic …

Introduction Therapeutic effects of cannabidiol (CBD) in specialized populations continue to
emerge. Despite supra-physiological dosing being shown to be tolerable in various …

Introduction The use and availability of oral and inhalable products containing cannabidiol
(CBD) as the principal constituent has increased with expanded cannabis/hemp …

Data supporting the physiological effects of cannabidiol (CBD) ingestion in humans are
conflicting. Differences between CBD preparations and bioavailability may contribute to …

Introduction Cannabidiol (CBD) is a phytocannabinoid found in the Cannabis plant. CBD
has received significant medical attention in relation to its anticonvulsant, anxiolytic, and …

Rigorous, controlled evidence for the therapeutic efficacy of CBD is lacking for many health
conditions. Possible concerns with the use of CBD as a therapeutic include the potential for …