Tumor-associated macrophages (TAMs) are involved in tumor progression and poor
prognosis in several malignancies. We previously demonstrated the interaction between …

Abstract CXCL6, contraction of C‐X‐C motif chemokine ligand 6, whose biological roles
have been rarely described in esophageal squamous cell carcinoma (ESCC). To …

CXCL8, a member of CXC chemokines, was constitutively expressed in many types of
human cancers, and its overexpression has been shown to play a critical role in promoting …

CXCL10 was recently shown to exert antimalignancy functions by influencing the tumor
microenvironment. Here, we have taken a different approach, investigating the effects of …

Background The chemokine CXCL12 and its corresponding receptor CXCR4 are key
players in the development of several cancers. Therefore, we hypothesized that there is a …

CXCL8 belongs to proinflammatory chemokines that are predominantly involved in
neutrophil chemotaxis and degranulation. Several studies have suggested that secretion of …

Background Metastasis is a major cause of death in human colorectal cancer patients.
However, the contribution of chemokines in the tumor microenvironment to tumor metastasis …

Upregulation of CXCR2 in tumor cells has been documented in several types of cancer. As
one of its ligands, CXCL5 is associated with neutrophil infiltration and poor prognosis in …

The present study was to identify abnormal methylation genes implicated in esophageal
squamous cell carcinoma (ESCC). Genomic methylation alterations in ESCC tissues were …

Deregulated expression of chemokines in tumor microenvironment contributes to tumor
metastasis by targeting distinct cells. Epithelial-derived neutrophil-activating peptide-78 …