Colorimetric detection of DNA using unmodified metallic nanoparticles and peptide nucleic acid probes

R Kanjanawarut, X Su - Analytical chemistry, 2009 - ACS Publications
We have developed a colorimetric assay for DNA detection based on the aggregation of
unmodified metallic nanoparticles. Charge neutral peptide nucleic acids (PNA) are used as …

[引用][C] Label‐Free Colorimetric Detection of Small Molecules Utilizing DNA Oligonucleotides and Silver Nanoparticles

X Xu, J Wang, F Yang, K Jiao, X Yang - Small, 2009 - Wiley Online Library
Since the use of DNA oligonucleotide–gold nanoparticle (AuNP) conjugates was pioneered
by Mirkin's group,[1] colorimetric assays based on DNA/AuNPs have been well developed in …

Enzyme-free colorimetric detection of DNA by using gold nanoparticles and hybridization chain reaction amplification

P Liu, X Yang, S Sun, Q Wang, K Wang… - Analytical …, 2013 - ACS Publications
A novel, high sensitive, and specific DNA assay based on gold nanoparticle (AuNP)
colorimetric detection and hybridization chain reaction (HCR) amplification has been …

Gold nanoparticles with asymmetric polymerase chain reaction for colorimetric detection of DNA sequence

H Deng, Y Xu, Y Liu, Z Che, H Guo, S Shan… - Analytical …, 2012 - ACS Publications
We developed a novel strategy for rapid colorimetric analysis of a specific DNA sequence by
combining gold nanoparticles (AuNPs) with an asymmetric polymerase chain reaction (As …

Homogeneous detection of nucleic acids based upon the light scattering properties of silver-coated nanoparticle probes

X Xu, DG Georganopoulou, HD Hill… - Analytical …, 2007 - ACS Publications
Herein we report the development of a simple, rapid, homogeneous, and sensitive detection
system for DNA based on the scattering properties of silver-amplified gold nanoparticle …

Gold nanoparticles as novel label for DNA diagnostics

A Csáki, R Möller, W Fritzsche - Expert Review of Molecular …, 2002 - Taylor & Francis
The growing interest in DNA diagnostics, especially in combination with the need for highly-
paralleled and miniaturized hybridization assays, is today addressed by fluorescence DNA …

UV–visible spectroscopy-based quantification of unlabeled DNA bound to gold nanoparticles

BL Baldock, JE Hutchison - Analytical chemistry, 2016 - ACS Publications
DNA-functionalized gold nanoparticles have been increasingly applied as sensitive and
selective analytical probes and biosensors. The DNA ligands bound to a nanoparticle …

Dissecting the effect of salt for more sensitive label-free colorimetric detection of DNA using gold nanoparticles

S Hu, PJJ Huang, J Wang, J Liu - Analytical Chemistry, 2020 - ACS Publications
Taking advantage of the protection effect of single-stranded DNA oligonucleotides, gold
nanoparticles (AuNPs) remain dispersed and retain a red color with the addition of a low …

A two-color-change, nanoparticle-based method for DNA detection

YC Cao, R Jin, CS Thaxton, CA Mirkin - Talanta, 2005 - Elsevier
Herein, we describe the detailed synthesis of Ag/Au core-shell nanoparticles, the surface-
functionalization of these particles with thiolated oligonucleotides, and their subsequent use …

Nanoparticle-based detection and quantification of DNA with single nucleotide polymorphism (SNP) discrimination selectivity

WJ Qin, LYL Yung - Nucleic acids research, 2007 - academic.oup.com
Sequence-specific DNA detection is important in various biomedical applications such as
gene expression profiling, disease diagnosis and treatment, drug discovery and forensic …