Summary Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell
responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance …

Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …

Although it has been more than 2 years since the start of the coronavirus disease 2019
(COVID-19) pandemic, COVID-19 continues to be a worldwide health crisis. Despite the …

Importance An ongoing outbreak of COVID-19 has exhibited significant threats around the
world. We found a significant decrease of T lymphocyte subsets and an increase of …

The exaggerated immune response induced in the lower respiratory tract against
coronaviruses (CoVs), including CoViD-19 (2019-nCoV), appears to contribute to the …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major public health
issue. COVID-19 is considered an airway/multi-systemic disease, and demise has been …

Abstract Objectives SARS-CoV-2 T-cell response characterization represents a crucial issue
for defining the role of immune protection against COVID-19. The aim of the study was to …

Class II tetramer reagents for eleven common DR alleles and a DP allele prevalent in the
world population were used to identify SARS-CoV-2 CD4+ T cell epitopes. A total of 112, 28 …

Background Although immune modulation is a promising therapeutic avenue in coronavirus
disease 2019 (COVID-19), the most relevant targets remain to be found. COVID-19 has …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can trigger a cytokine
storm in the pulmonary tissue by releasing various types of mediators, leading to acute …