D Britton, Y Zen, A Quaglia, S Selzer, V Mitra… - PLoS …, 2014 - journals.plos.org
Objective LC-MS/MS phospho-proteomics is an essential technology to help unravel the complex molecular events that lead to and propagate cancer. We have developed a global …
D Lv, D Li, Y Cai, J Guo, S Chu, J Yu, K Liu… - Nucleic Acids …, 2024 - academic.oup.com
Advancements in mass spectrometry (MS)-based proteomics have greatly facilitated the large-scale quantification of proteins and microproteins, thereby revealing altered signalling …
T Guo, SS Lee, WH Ng, Y Zhu, CS Gan, J Zhu… - Cellular and Molecular …, 2011 - Springer
Abstract We integrated LC-MS/MS-based and protein antibody array-based proteomics with genomics approaches to investigate the phosphoproteome and transcriptome of gastric …
J Zou, Z Qin, R Li, X Yan, H Huang, B Yang… - Molecular & Cellular …, 2024 - ASBMB
Large-scale omics studies have generated a wealth of mass spectrometry–based proteomics data, which provide additional insights into disease biology spanning genomic …
Background Proteomic characterization of cancers is essential for a comprehensive understanding of key molecular aberrations. However, proteomic profiling of a large cohort …
Z Wang, H Liu, Y Yan, X Yang, Y Zhang… - Journal of proteome …, 2020 - ACS Publications
Breast cancer is one of the most common cancers in women worldwide. In the past decades, many advances have been made in understanding and treating breast cancer. However …
Quantitative proteomics allows the characterization of molecular changes between healthy and disease states. To interpret such datasets, their integration to the protein–protein …
A Abramowicz, A Wojakowska… - Journal of translational …, 2015 - Springer
Background The gastric cancer is one of the most common and mortal cancer worldwide. The initial asymptomatic development and further nonspecific symptoms result in diagnosis …
Global proteomic data generated by advanced mass spectrometry (MS) technologies can help bridge the gap between genome/transcriptome and functions and hold great potential …