A scalable ISFET sensing and memory array with sensor auto-calibration for on-chip real-time DNA detection

N Moser, J Rodriguez-Manzano… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
This paper presents a novel CMOS-based system-onchip with a 78× 56 ion-sensitive field-
effect transistor array using in-pixel quantization and compensation of sensor nonidealities …

A dual-sensing thermo-chemical ISFET array for DNA-based diagnostics

M Cacho-Soblechero… - … Circuits and Systems, 2020 - ieeexplore.ieee.org
This paper presents a 32× 32 ISFET array with inpixel dual-sensing and programmability
targeted for on-chip DNA amplification detection. The pixel architecture provides thermal …

A 12.8 k current-mode velocity-saturation ISFET array for on-chip real-time DNA detection

N Miscourides, LS Yu… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
This paper presents a large-scale CMOS chemicalsensing array operating in current mode
for real-time ion imaging and detection of DNA amplification. We show that the currentmode …

ISFET-based sensing and electric field actuation of DNA for on-chip detection: A review

L Keeble, N Moser, J Rodriguez-Manzano… - IEEE Sensors …, 2020 - ieeexplore.ieee.org
The advent of complementary metal-oxide-semiconductor (CMOS) based lab-on-chip (LoC)
technology, which combines on-chip sample handling with integrated sensing, heralds the …

A robust ISFET pH-measuring front-end for chemical reaction monitoring

Y Hu, P Georgiou - IEEE Transactions on Biomedical Circuits …, 2014 - ieeexplore.ieee.org
This paper presents a robust, low-power and compact ion-sensitive field-effect transistor
(ISFET) sensing front-end for pH reaction monitoring using unmodified CMOS. Robustness …

A dual-mode large-arrayed CMOS ISFET sensor for accurate and high-throughput pH sensing in biomedical diagnosis

X Huang, H Yu, X Liu, Y Jiang, M Yan… - IEEE Transactions on …, 2015 - ieeexplore.ieee.org
Goal: The existing ISFET-based DNA sequencing detects hydrogen ions released during the
polymerization of DNA strands on microbeads, which are scattered into microwell array …

An integrated ISFET sensor array

K Nakazato - Sensors, 2009 - mdpi.com
A monolithically integrated ISFET sensor array and interface circuit are described. A new
high-density, low-power source-drain follower was developed for the sensor array. ISFETs …

Optimization of CMOS-ISFET-based biomolecular sensing: analysis and demonstration in DNA detection

G Xu, J Abbott, D Ham - IEEE Transactions on Electron Devices, 2016 - ieeexplore.ieee.org
Ion-sensitive field-effect transistors (ISFETs) have been used to detect a variety of
biomolecules whose charges alter the current or threshold voltage of the transistor. ISFETs …

Sensor arrays for fully-electronic DNA detection on CMOS

R Thewes, F Hofmann, A Frey… - … Solid-State Circuits …, 2002 - ieeexplore.ieee.org
A 16× 8 DNA sensor array chip with fully electronic readout is based on an extended CMOS
process. Requirements concerning the integration of bio-compatible interface-, sensor-and …

Fully electronic DNA detection on a CMOS chip: device and process issues

F Hofmann, A Frey, B Holzapfl… - Digest. International …, 2002 - ieeexplore.ieee.org
A sensor array for fully electronic detection of DNA molecules is fabricated using an
extended CMOS process. A gold deposition process module and a compartment are …