JT O'Brien - International Journal of Geriatric Psychiatry, 1995 - psycnet.apa.org
Reviews recent magnetic resonance imaging (MRI) studies suggesting that temporal lobe and, in particular, hippocampal atrophy may be a marker for Alzheimer's disease (AD). The …
G Aël Chetelat, JC Baron - Neuroimage, 2003 - Elsevier
To accurately predict the development of Alzheimer's disease (AD) at its predementia stage would be a major breakthrough from both therapeutic and research standpoints. In this …
NC Fox, EK Warrington, PA Freeborough… - Brain, 1996 - academic.oup.com
The hippocampal formation (HF) is known from pathological and MRI studies to be severely atrophied in established Alzheimer's disease. However, it is unclear when the earliest …
BB Yavuz, S Ariogul, M Cankurtaran… - International …, 2007 - cambridge.org
Background: The aim of this study is to compare the results of magnetic resonance (MR) imaging, particularly the decline in hippocampal volume, of patients with Alzheimer's …
MP Laakso, H Soininen, K Partanen, M Lehtovirta… - Neurobiology of …, 1998 - Elsevier
In this study, magnetic resonance imaging (MRI) of the hippocampus for the diagnosis of early Alzheimer's disease (AD) is evaluated. We measured hippocampal volumes and the …
MJ de Leon, A Convit, S DeSanti… - International …, 1997 - cambridge.org
There is compelling evidence for the early involvement of the hippocampal formation in the natural history of Alzheimer's disease (AD). The evidence comes from recent …
Atrophy patterns on MRI can reliably predict three neuropathological subtypes of Alzheimer's disease (AD): typical, limbic-predominant, or hippocampal-sparing. A method to …
CR Jack Jr, DW Dickson, JE Parisi, YC Xu, RH Cha… - Neurology, 2002 - AAN Enterprises
Objectives: To assess the diagnostic specificity of MRI-defined hippocampal atrophy for AD among individuals with a variety of pathologically confirmed conditions associated with …
A Convit, MJ De Leon, J Golomb, AE George… - Psychiatric …, 1993 - Springer
We evaluated three groups of elderly individuals who were carefully screened to rule out clinically significant diseases that could affect cognition. They were matched for age and …