A new lanthanide chelating tag (M8) for paramagnetic labeling of biomolecules is presented,
which is based on an eight-fold, stereoselectively methyl-substituted DOTA that can be …

Lanthanide chelating tags (LCTs) have been used with great success for determining
structures and interactions of proteins and other biological macromolecules. Recently LCTs …

The design, synthesis and evaluation of four novel lanthanide-binding tags for paramagnetic
NMR spectroscopy are reported. Each tag is based on the ((2S, 2′ S, 2′′ S, 2′′′ S) …

Abstract Here we present Cys-Ph-TAHA, a new nonadentate lanthanide tag for the
paramagnetic labelling of proteins. The tag can be easily synthesized and is …

Structural studies of proteins and protein–ligand complexes by nuclear magnetic resonance
(NMR) spectroscopy can be greatly enhanced by site-specific attachment of lanthanide ions …

Site‐specific labeling of proteins with paramagnetic lanthanides offers unique opportunities
by virtue of NMR spectroscopy in structural biology. In particular, these paramagnetic data …

A two‐thiol reactive lanthanide–DOTA (1, 4, 7, 10‐tetraazacyclododecane‐N, N′, N′′,
N′′′‐tetraacetic acid) chelate, CLaNP‐3 (CLaNP= caged lanthanide NMR probe), was …

Lanthanide-binding tags (LBTs) are peptide sequences of up to 20 encoded amino acids
that tightly and selectively complex lanthanide ions and can sensitize terbium (Tb3+) …

Paramagnetic lanthanides ions are broadly used in NMR spectroscopy. The effects of
unpaired electrons on NMR spectral parameters provide a powerful tool for the …

A new lanthanide tag was designed for site-specific labeling of proteins with paramagnetic
lanthanide ions. The tag, 4-mercaptomethyl-dipicolinic acid, binds lanthanide ions with …