Gut Failure: A Review of the Pathophysiology and Therapeutic Potentials in the Gut–Heart Axis

D Matsiras, S Bezati, I Ventoulis, C Verras… - Journal of Clinical …, 2023 - mdpi.com
Despite considerable advances in the field, heart failure (HF) still poses a significant disease
burden among affected individuals since it continues to cause high morbidity and mortality …

[HTML][HTML] The gut in heart failure: Current knowledge and novel frontiers

A Gallo, N Macerola, AM Favuzzi… - Medical Principles and …, 2022 - karger.com
Heart failure (HF) represents a major health problem affecting millions of people worldwide.
In the latest years, many efforts have been made to search for more effective strategies to …

Heart Failure: a Punch from the Gut

A Mahenthiran, J Wilcox, WHW Tang - Current Heart Failure Reports, 2024 - Springer
Abstract Purpose of Review This article seeks to elucidate the mechanisms underlying the
bidirectional relationship between the gut and the heart, focusing on the pathophysiology of …

The gut microbiome and heart failure: a better gut for a better heart

M Branchereau, R Burcelin, C Heymes - Reviews in Endocrine and …, 2019 - Springer
Despite the development of new drugs and therapeutic strategies, mortality and morbidity
related to heart failure (HF) remains high. It is also the leading cause of global mortality …

The emerging role of the gut in chronic heart failure

A Sandek, M Rauchhaus, SD Anker… - Current Opinion in …, 2008 - journals.lww.com
It remains unclear whether increased adherent bacteria in patients with chronic heart failure
are a primary or secondary event and whether they contribute to systemic inflammation. Both …

Gut microbiota in heart failure and related interventions

AT Chen, J Zhang, Y Zhang - Imeta, 2023 - Wiley Online Library
Heart failure (HF) is a sophisticated syndrome with structural or functional impairment of
ventricular filling or ejection of blood, either causing symptoms and signs or being …

The gut and intestinal bacteria in chronic heart failure

A Sandek, SD Anker, S Haehling - Current drug metabolism, 2009 - ingentaconnect.com
Chronic heart failure (CHF) is now recognized as a multisystem disorder with increased
sympathetic tone, hormonal derangements, an anabolic/catabolic imbalance, endothelial …

The emerging role of gut dysbiosis in cardio-metabolic risk factors for heart failure

Y Sata, FZ Marques, DM Kaye - Current Hypertension Reports, 2020 - Springer
Abstract Purpose of Review To summarize the recent evidence that supports a role for the
gut microbiota, microbiota-derived metabolites, and dysbiosis on cardiovascular risk factors …

The Role of Gut Microbiota and the Potential Effects of Probiotics in Heart Failure

C Petruzziello, A Saviano, LL Manetti, N Macerola… - Medicina, 2024 - mdpi.com
Heart failure (HF) remains a significant global health challenge, affecting millions of
individuals worldwide and posing a substantial burden on healthcare systems. HF is a …

Design of the GutHeart—targeting gut microbiota to treat heart failure—trial: a Phase II, randomized clinical trial

CCK Mayerhofer, AO Awoyemi… - ESC Heart …, 2018 - Wiley Online Library
Aims Heart failure (HF) is a multifactorial disease. Current treatments target only a fraction of
the putative pathophysiological pathways. In patients with HF, reduced cardiac output and …