Mice injected with monoclonal antibody to the L3T4+ (CD4+) cell membrane surface
glycoprotein of T lymphocytes and immunized with antigens of Trypanosoma cruzi had …

The sensitivity of host (circulating) forms of T. cruzi to cell-mediated immunological
destruction and requirements for the reaction were examined. Both human and mouse …

The role of antibodies and the host's antibody-forming capacity in resistance to
Trypanosoma cruzi infection has been investigated in the Biozzi high and low responder …

C57BL/6 mice exhibit low parasitemias and often survive Trypanosoma cruzi infections,
whereas C3H (He) mice die during the acute phase with relatively high parasitemias. The …

Inbred C57BL/10 mice immunized with live culture forms of Trypanosoma cruzi were
resistant to acute infection after challenge with bloodstream forms. Splenic leukocytes or …

The role of T cell populations in immune control of Trypanosoma cruzi infection and
subsequent development of disease has been examined using gene knockout mice …

The role of CD8+ T cells in immune control of Trypanosoma cruzi infection in mice was
examined by using in vivo depletion of CD8+ T cells with antibodies. Both the resistant …

Recent in vivo depletion studies in mice demonstrated that CD8+ T cells play a critical role in
acute resistance to experimental Trypanosoma cruzi infections. As part of efforts to …

Trypanosoma cruzi Infections l thank Dr Kierszenbaum for highlighting the complexities of
the participation of CD8* T cells in immunity and patho-genesis in Trypanosoma cruzi …

Infection with Trypanosoma cruzi results in the development of both type 1 and type 2
patterns of cytokine responses during acute and chronic stages of infection. To investigate …