The preimplantation development of the mammalian embryo encompasses a series of
critical events: the transition from oocyte to embryo, the first cell divisions, the establishment …

Studies using low-resolution methods to assess gene expression during preimplantation
mouse development indicate that changes in gene expression either precede or occur …

The mouse embryo is the canonical model for mammalian preimplantation development.
Recent advances in single cell profiling allow detailed analysis of embryogenesis in other …

Mammalian pre-implantation development is a complex process involving dramatic changes
in the transcriptional architecture,,,. We report here a comprehensive analysis of …

Pre-implantation embryo development is an intricate and precisely regulated process
orchestrated by maternally inherited proteins and newly synthesized proteins following …

Naive pluripotency is manifest in the preimplantation mammalian embryo. Here we
determine transcriptome dynamics of mouse development from the eight-cell stage to …

Successful human development is dependent upon a cascade of events following
fertilization. Unfortunately, knowledge of these critical events in humans is remarkably …

Background Preimplantation development is a crucial step in early human development.
However, the molecular basis of human preimplantation development is not well known …

Recent years have seen exciting progress across human embryo research, including new
methods for culturing embryos, transcriptional profiling of embryogenesis and gastrulation …

Background During mammalian pre-implantation embryonic development dramatic and
orchestrated changes occur in gene transcription. The identification of the complete changes …