[HTML][HTML] Immunopathology of SARS-CoV-2 infection: immune cells and mediators, prognostic factors, and immune-therapeutic implications

A Allegra, M Di Gioacchino, A Tonacci… - International journal of …, 2020 - mdpi.com
The present is a comprehensive review of the immunopathology of Covid-19. The immune
reaction to SARS-CoV-2 infection is characterized by differentiation and proliferation of a …

[HTML][HTML] Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position …

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …

COVID‐19: Consider IL‐6 receptor antagonist for the therapy of cytokine storm syndrome in SARS‐CoV‐2 infected patients

C Chakraborty, AR Sharma… - Journal of medical …, 2020 - Wiley Online Library
COVID‐19 leads to mortality of several patients and the cytokine storm is reportedly critical
in the patients. To reduce the cytokine storm, we would like to propose the interleukin (IL) 6 …

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …

An enlightening role for cytokine storm in coronavirus infection

Z Zhao, Y Wei, C Tao - Clinical Immunology, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in Wuhan,
China has dispersed rapidly worldwide. Although most patients present with mild fever …

[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

[HTML][HTML] Immunomodulation for severe COVID-19 pneumonia: the state of the art

Y Zhang, Y Chen, Z Meng - Frontiers in immunology, 2020 - frontiersin.org
COVID-19 has become a worldwide pandemic caused by the novel coronavirus named
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Severe cases of COVID-19 …

Immune responses and pathogenesis of SARS‐CoV‐2 during an outbreak in Iran: comparison with SARS and MERS

M Rokni, V Ghasemi, Z Tavakoli - Reviews in medical virology, 2020 - Wiley Online Library
The beginning of 2020 has seen the emergence of COVID‐19, an outbreak caused by a
novel coronavirus, SARS‐CoV‐2, an important pathogen for humans. There is an urgent …

COVID-19 as an acute inflammatory disease

RH Manjili, M Zarei, M Habibi… - The journal of immunology, 2020 - journals.aai.org
Abstract The 2019 coronavirus disease (COVID-19) pandemic caused by the virus severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has created an unprecedented …

[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
The recent novel coronavirus disease (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is seeing a rapid increase in infected …