Objective: To assess whether combination antibiotic therapy improves outcome of severe
community-acquired pneumonia in the subset of patients with shock. Design: Secondary …

Background It remains uncertain why immunocompetent patients with bacterial community-
acquired pneumonia (CAP) die, in spite of adequate antibiotics. Methods This is a …

Background: Septic shock represents the major cause of infection-associated mortality in the
intensive care unit. The possibility that combination antibiotic therapy of bacterial septic …

Introduction We aimed to compare intensive care unit mortality due to non-pneumococcal
severe community-acquired pneumonia between the periods 2000–2002 and 2008–2014 …

Community-acquired pneumonia (CAP) is a common and potentially serious illness that is
associated with morbidity and mortality. Although medical care has improved during the past …

Objective To assess the effect on survival of macrolides or fluoroquinolones in intubated
patients admitted to the intensive care unit (ICU) with severe community-acquired …

Antibiotic therapy (AT) is the cornerstone of the management of severe community-acquired
pneumonia (CAP). However, the best treatment strategy is far from being established. To …

Objective: To assess whether a potential benefit with combination antibiotic therapy is
restricted to the most critically ill subset of patients, particularly those with septic shock. Data …

In order to determine whether combination antibiotic therapy decreases mortality after
severe pneumococcal infection, a retrospective study of a cohort of 1,840 adult patients with …

Objectives Our primary goal was to evaluate the impact on in-hospital mortality rate of
adequate empirical antibiotic therapy, after controlling for confounding variables, in a cohort …