Intestinal conversion of the isoflavone daidzein to the bioactive equol is exclusively
catalyzed by gut bacteria, but a direct role in equol formation under in vivo conditions has …

The intestinal microbial transformation of daidzein, one of the principal isoflavones from soy,
into the isoflavan equol is subjected to a high interindividual variability. The latter compound …

The metabolism of isoflavones by gut bacteria plays a key role in the availability and
bioactivation of these compounds in the intestine. Daidzein and genistein are the most …

Gut bacteria play a key role in the metabolism of dietary isoflavones, thereby influencing the
availability and bioactivation of these polyphenols in the intestine. The human intestinal …

Equol is a metabolite of isoflavone daidzein and has an affinity to estrogen receptors.
Although equol is produced by intestinal bacteria, the association between the status of …

Hydroxy-3-(4′-hydroxyphenyl)-chroman (S-equol) is a specific end-metabolite formed in
the biotransformation of the dietary soy isoflavones daidzin and daidzein by intestinal …

Human health benefits are expected of the anti-estrogenic or estrogenic effects of soy
isoflavone. Recently, the biological effects of one of the metabolites of soy isoflavone, equol …

Soy isoflavones have received considerable attention. Individuals with isoflavones‐rich diets
have significantly lower occurrences of cardiovascular disease, osteoporosis, and some …

Isoflavones are found in leguminous plants, especially soybeans. They have a structural
similarity to natural estrogens, which enables them to bind to estrogen receptors and elicit …

Epidemiological data suggest that regular intake of isoflavones from soy reduces the
incidence of estrogen-dependent and aging-associated disorders, such as menopause …