The role of Th17 response in COVID-19

D Martonik, A Parfieniuk-Kowerda, M Rogalska… - Cells, 2021 - mdpi.com
COVID-19 is an acute infectious disease of the respiratory system caused by infection with
the SARS-CoV-2 virus (Severe Acute Respiratory Syndrome Coronavirus 2). Transmission …

Neutrophils mediate Th17 promotion in COVID-19 patients

Z Parackova, M Bloomfield, A Klocperk… - Journal of Leucocyte …, 2021 - academic.oup.com
From the beginning of 2020, an urgent need to understand the pathophysiology of SARS-
CoV-2 disease (COVID-19), much of which is due to dysbalanced immune responses …

Th17 and Treg cells function in SARS‐CoV2 patients compared with healthy controls

A Sadeghi, S Tahmasebi, A Mahmood… - Journal of cellular …, 2021 - Wiley Online Library
In the course of the coronavirus disease 2019 (COVID‐19), raising and reducing the function
of Th17 and Treg cells, respectively, elicit hyperinflammation and disease progression. The …

Inflammatory cytokine: IL-17A signaling pathway in patients present with COVID-19 and current treatment strategy

T Shibabaw - Journal of inflammation research, 2020 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) is a globally communicable public health
disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV-2) …

A case for targeting Th17 cells and IL-17A in SARS-CoV-2 infections

M Orlov, PL Wander, ED Morrell… - The Journal of …, 2020 - journals.aai.org
Abstract SARS-CoV-2, the virus causing COVID-19, has infected millions and has caused
hundreds of thousands of fatalities. Risk factors for critical illness from SARS-CoV-2 infection …

COVID‐19 immunopathology with emphasis on Th17 response and cell‐based immunomodulation therapy: potential targets and challenges

A Pourgholaminejad… - Scandinavian Journal …, 2022 - Wiley Online Library
The role of the immune system against coronavirus disease 2019 (COVID‐19) is unknown in
many aspects, and the protective or pathologic mechanisms of the immune response are …

Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

S De Biasi, M Meschiari, L Gibellini, C Bellinazzi… - Nature …, 2020 - nature.com
The immune system of patients infected by SARS-CoV-2 is severely impaired. Detailed
investigation of T cells and cytokine production in patients affected by COVID-19 pneumonia …

T-helper cell subset response is a determining factor in COVID-19 progression

FJ Gil-Etayo, P Suàrez-Fernández… - Frontiers in cellular …, 2021 - frontiersin.org
The immune response type organized against viral infection is determinant in the prognosis
of some infections. This work has aimed to study Th polarization in acute COVID-19 and its …

[HTML][HTML] TH17 responses in cytokine storm of COVID-19: An emerging target of JAK2 inhibitor Fedratinib

D Wu, XO Yang - Journal of Microbiology, Immunology and Infection, 2020 - Elsevier
COVID-19 emerges as a pandemic disease with high mortality. Development of effective
prevention and treatment is an urgent need. We reviewed TH17 responses in patients with …

May IL-17 have a role in COVID-19 infection?

M Megna, M Napolitano, G Fabbrocini - Medical hypotheses, 2020 - ncbi.nlm.nih.gov
SARS-Corona-Virus-2 related disease (COVID-19) which started in Wuhan, China on
December 2019, is spreading rapidly throughout the world [1]. COVID-19 clinical spectrum is …