Polymorphism, intermolecular interactions, and spectroscopic properties in crystal structures of sulfonamides

CI Sainz-Díaz, M Francisco-Márquez… - Journal of …, 2018 - Elsevier
The antibiotics family of sulfonamides has been used worldwide intensively in human
therapeutics and farm livestock during decades. Intermolecular interactions of these …

Crystal polymorphism and spectroscopical properties of sulfonamides in solid state by means of First Principles calculations

CI Sainz-Díaz, AP de la Luz… - Journal of Computer …, 2022 - Springer
Sulfonamides are an important class of therapeutic agents. The increase in the number of
new sulfonamide derivatives makes it necessary to study more rationally the chemical …

Experimental and computational insights into polymorphism in an antimicrobial sulfadrug: discovery of a novel monoclinic form of sulfamerazine

A Direm, C Parlak, B El Bali, MSM Abdelbaky… - Journal of the Iranian …, 2024 - Springer
Abstract Sulfamerazine (4-Amino-N-(4-methylpyrimidin-2-yl) benzenesulfonamide) is a
polymorphic molecule crystallizing in three forms: Form I: Pn 21 a polymorph (with three …

[HTML][HTML] Tautomerism and IR spectroscopy of arylsulfonamides by quantum mechanical calculations

FM Misaela, P de la Luz Alexander, SC Catalina… - Journal of Molecular …, 2022 - Elsevier
The molecular structures of sulphonamides are interesting for evaluating their mobility in
soils and preparing composite complexes for optimizing the use of these drugs. In this work …

Using small molecule crystal structure data to obtain information about sulfonamide conformation

A Parkin, A Collins, CJ Gilmore… - … Section B: Structural …, 2008 - journals.iucr.org
Understanding the conformations adopted by the sulfonamide group is essential to the
understanding of the way that sulfa drugs act upon the body. The relative energies of these …

Synthesis, crystal and molecular structure of two biologically active aromatic sulfonamides and their hydrochloride salts

M Remko, J Kožíšek, J Semanová, F Gregáň - Journal of Molecular …, 2010 - Elsevier
4-Sulfamoyl-N-(3-morpholinopropyl) benzamide (P10), N-(3-morpholinopropyl) benzene-1,
4-disulfonamide (P20) and their hydrochloride salts (P11 and P22) were prepared. The X …

Quantitative analysis of weak interactions by Lattice energy calculation, Hirshfeld surface and DFT studies of sulfamonomethoxine

KD Patel, UH Patel - Journal of Molecular Structure, 2017 - Elsevier
Abstract Sulfamonomethoxine, 4-Amino-N-(6-methoxy-4-pyrimidinyl) benzenesulfonamide
(C 11 H 12 N 4 O 3 S), is investigated by single crystal X-ray diffraction technique. Pair of N …

Thermodynamic and structural aspects of sulfonamide crystals and solutions

GL Perlovich, VV Tkachev, NN Strakhova… - Journal of …, 2009 - Elsevier
The crystal structures of three sulfonamides with the general structure 4‐NH 2‐C 6 H 4‐SO 2
NH‐C 6 H 4/3‐R (R= 4‐Et; 4‐OMe; 5‐Cl‐2‐Me) have been determined by X‐ray diffraction …

A study of sulfamerazine single crystals using atomic force microscopy, transmission light microscopy, and Raman spectroscopy

X Cao, C Sun, TJ Thamann - Journal of pharmaceutical sciences, 2005 - Elsevier
ABSTRACT Sulfamerazine (SMZ) Form I and II single crystals were prepared from aqueous
dispersions of SMZ bulk samples and studied using several microscopic and spectroscopic …

Conformational polymorphism VI: The crystal and molecular structures of Form II, Form 111, and Form V of 4-Amino-N-2-pyridinylbenzenesulfonamide (Sulfapyridine)

I Bar, J Bernstein - Journal of pharmaceutical sciences, 1985 - Elsevier
The crystal structures of three crystalline forms of 4-amino-N-pyridinylbenzenesulfonamide
(sulfapyridine) have been determined by X-ray single crystal structure analysis. Form II …