Aging, exceptional longevity and comparisons of the Hannum and Horvath epigenetic clocks

NJ Armstrong, KA Mather, A Thalamuthu, MJ Wright… - …, 2017 - Taylor & Francis
Aim: To examine the relationships between two epigenetic clocks, aging and exceptional
longevity. Materials & methods: Participants were from three adult cohorts with blood DNA …
被引用次数：79 相关文章 所有 7 个版本
[PDF] oup.com

Tracking the epigenetic clock across the human life course: a meta-analysis of longitudinal cohort data

RE Marioni, M Suderman, BH Chen… - The Journals of …, 2019 - academic.oup.com
Background Epigenetic clocks based on DNA methylation yield high correlations with
chronological age in cross-sectional data. Due to a paucity of longitudinal data, it is not …
被引用次数：94 相关文章 所有 14 个版本
[PDF] springer.com

Does the epigenetic clock GrimAge predict mortality independent of genetic influences: an 18 year follow-up study in older female twin pairs

T Föhr, K Waller, A Viljanen, R Sanchez… - Clinical …, 2021 - Springer
Background Epigenetic clocks are based on DNA methylation (DNAm). It has been
suggested that these clocks are useable markers of biological aging and premature …
被引用次数：27 相关文章 所有 18 个版本
[PDF] springer.com

Systematic underestimation of the epigenetic clock and age acceleration in older subjects

LY El Khoury, T Gorrie-Stone, M Smart, A Hughes… - Genome biology, 2019 - Springer
Abstract Background The Horvath epigenetic clock is widely used. It predicts age quite well
from 353 CpG sites in the DNA methylation profile in unknown samples and has been used …
被引用次数：92 相关文章 所有 20 个版本
[HTML] nih.gov

[HTML][HTML] Centenarians consistently present a younger epigenetic age than their chronological age with four epigenetic clocks based on a small number of CpG sites

A Daunay, LM Hardy, Y Bouyacoub… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Aging is a progressive time-dependent biological process affecting differentially individuals,
who can sometimes present exceptional longevity. Epigenetic alterations are one of the …
被引用次数：15 相关文章 所有 11 个版本
[PDF] oup.com

The association between epigenetic clocks and physical functioning in older women: a 3-year follow-up

T Föhr, T Törmäkangas, H Lankila… - The Journals of …, 2022 - academic.oup.com
Background Epigenetic clocks are composite markers developed to predict chronological
age or mortality risk from DNA methylation (DNAm) data. The present study investigated the …
被引用次数：11 相关文章 所有 11 个版本
[PDF] springer.com

Leisure-time physical activity and DNA methylation age—a twin study

E Sillanpää, M Ollikainen, J Kaprio, X Wang… - Clinical …, 2019 - Springer
Background Epigenetic clocks may increase our understanding on human aging and how
genetic and environmental factors regulate an individual aging process. One of the most …
被引用次数：49 相关文章 所有 21 个版本
[PDF] springer.com

Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden

RF Hillary, AJ Stevenson, DL McCartney… - Clinical …, 2020 - Springer
Background Individuals of the same chronological age display different rates of biological
ageing. A number of measures of biological age have been proposed which harness age …
被引用次数：130 相关文章 所有 22 个版本
[PDF] springer.com

The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis

PD Fransquet, J Wrigglesworth, RL Woods, ME Ernst… - Clinical …, 2019 - Springer
Background Ageing is one of the principal risk factors for many chronic diseases. However,
there is considerable between-person variation in the rate of ageing and individual …
被引用次数：257 相关文章 所有 23 个版本

Epigenetic clock: A promising biomarker and practical tool in aging

R Duan, Q Fu, Y Sun, Q Li - Ageing Research Reviews, 2022 - Elsevier
As a complicated process, aging is characterized by various changes at the cellular,
subcellular and nuclear levels, one of which is epigenetic aging. With increasing awareness …
被引用次数：76 相关文章 所有 3 个版本