Recent advances in molecular biology, neurobiology, genetics, and imaging have
demonstrated important insights about the nature of neurological diseases. However, a …

This book provides an entry point into Systems Biology for researchers in genetics,
molecular biology, cell biology, microbiology and biomedical science to understand the key …

In this paper we raise 'ten questions' broadly related to 'omics', the term systems biology, and
why the new biology has failed to deliver major therapeutic advances for many common …

Genetic and genomic approaches have implicated hundreds of genetic loci in
neurodevelopmental disorders and neurodegeneration, but mechanistic understanding …

Systems biology interdisciplinary approaches have become an essential analytical tool that
may yield novel and powerful insights about the nature of human health and disease …

Abstract Systems biology represents an experimental approach to biology that attempts to
study biological systems in a holistic rather than an atomistic manner. Ideally this involves …

Because of the complexity inherent in biological systems, many researchers frequently rely
on a combination of global analysis and computational approaches to gain insight into both …

Neurodegenerative diseases (NDs) collectively afflict more than 40 million people
worldwide. The majority of these diseases lack therapies to slow or stop progression due in …

Abstract Systems biology, possibly the latest sub-discipline of biology, has arisen as a result
of the shockwave of genomic and proteomic data that has appeared in the past few years …

Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis are pressing health concerns in modern societies for which …