The development of a nanoparticle-based detection methodology for sensitive and specific
DNA-based diagnostic applications is described. The technology utilizes gold nanoparticles …

Nucleic acid diagnostics is dominated by fluorescence-based assays that use complex and
expensive enzyme-based target or signal-amplification procedures,,,,,. Many clinical …

Simple, fast, economical, and sensitive detection of specific DNA sequences is crucial to
pathogen detection and biomedical research. We have designed a novel fluorescent assay …

A novel system for the detection of DNA hybridization in a homogeneous format is
developed. This method is based on fluorescence quenching by gold nanoparticles used as …

We report a simple, fast, and sensitive approach for visual detection of single-nucleotide
polymorphism (SNP) based on hairpin oligonucleotide-functionalized gold nanoparticle …

Herein we report the development of a simple, rapid, homogeneous, and sensitive detection
system for DNA based on the scattering properties of silver-amplified gold nanoparticle …

Herein, we describe the detailed synthesis of Ag/Au core-shell nanoparticles, the surface-
functionalization of these particles with thiolated oligonucleotides, and their subsequent use …

Sequence-specific DNA detection is important in various biomedical applications such as
gene expression profiling, disease diagnosis and treatment, drug discovery and forensic …

The highly specific molecular recognition properties of oligonucleotides are combined with
the unique optical properties of gold nanoparticles for the development of a dry-reagent strip …

The impact of advances in nanotechnology is particularly relevant in biodiagnostics, where
nanoparticle-based assays have been developed for specific detection of bioanalytes of …