Anxiety is linked to compromised interactions between the amygdala and the dorsal and
ventral medial prefrontal cortex (mPFC). While numerous task-based neuroimaging studies …

Functional neuroimaging implicates hyperactivity of amygdala-orbitofrontal circuitry as a
common neurobiological mechanism underlying the development of anxiety. Less is known …

Background: Neuroimaging research has traditionally explored fear and anxiety in response
to discrete threat cues (eg, during fear conditioning). However, anxiety is a sustained …

Anxiety is the most frequently co-occurring symptom with depression and subsequently
contributes to increased severity and treatment resistance in patients with major depressive …

Biomarkers of inflammation, including inflammatory cytokines and the acute-phase reactant
C-reactive protein (CRP), are reliably increased in a subset of patients with depression …

Social anxiety disorder patients suffer from excessive anxious responses in social
interaction leading to avoidance behavior and social impairment. Although the amygdala …

Background Anxiety produced by environmental threats can impair goal-directed processing
and is associated with a range of psychiatric disorders, particularly when aversive events …

Functionally, anxiety serves to increase vigilance towards aversive stimuli and improve the
ability to detect and avoid danger. We have recently shown, for instance, that anxiety …

Background Amygdala–prefrontal cortex (PFC) functional connectivity may be influenced by
anxiety and development. A prior study on anxiety found age‐specific dysfunction in the …

Anxiety is one of the most common mental states of humans. Although it drives us to avoid
frightening situations and to achieve our goals, it may also impose significant suffering and …